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Trafficking of endosomal Toll-like receptors

Over the last decade we have learned much about nucleic acid recognition by the innate immune system and in particular by Toll-like receptors (TLRs). These receptors localize to endosomal compartments where they are poised to recognize microbial nucleic acids. Multiple regulatory mechanisms function...

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Autors principals: Lee, Bettina L., Barton, Gregory M.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037363/
https://ncbi.nlm.nih.gov/pubmed/24439965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2013.12.002
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