Llwytho...

The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor

Mammalian Toll-like receptors (TLRs) 3, 7, 8 and 9 initiate immune responses to infection by recognizing microbial nucleic acids1, 2; however, these responses come at the cost of potential autoimmunity due to inappropriate recognition of self nucleic acid3. The localization of TLR9 and TLR7 to intra...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ewald, Sarah E., Lee, Bettina L., Lau, Laura, Wickliffe, Katherine E., Shi, Guo-Ping, Chapman, Harold A., Barton, Gregory M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596276/
https://ncbi.nlm.nih.gov/pubmed/18820679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07405
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