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The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor
Mammalian Toll-like receptors (TLRs) 3, 7, 8 and 9 initiate immune responses to infection by recognizing microbial nucleic acids1, 2; however, these responses come at the cost of potential autoimmunity due to inappropriate recognition of self nucleic acid3. The localization of TLR9 and TLR7 to intra...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2596276/ https://ncbi.nlm.nih.gov/pubmed/18820679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07405 |
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