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The Ectodomain of the Toll-like Receptor 4 Prevents Constitutive Receptor Activation
Toll-like receptor 4 (TLR4) is involved in activation of the innate immune response in a large number of different diseases. Despite numerous studies, the role of separate domains of TLR4 in the regulation of receptor activation is poorly understood. Replacement of the TLR4 ectodomain with LPS-bindi...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3123098/ https://ncbi.nlm.nih.gov/pubmed/21543336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.205419 |
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