STIM1 promotes migration, phagosomal maturation and antigen cross-presentation in dendritic cells

Antigen cross-presentation by dendritic cells (DC) stimulates cytotoxic T cell activation to promote immunity to intracellular pathogens, viruses and cancer. Phagocytosed antigens generate potent T cell responses, but the signalling and trafficking pathways regulating their cross-presentation are un...

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Publicado en:Nat Commun
Autores principales: Nunes-Hasler, Paula, Maschalidi, Sophia, Lippens, Carla, Castelbou, Cyril, Bouvet, Samuel, Guido, Daniele, Bermont, Flavien, Bassoy, Esen Y., Page, Nicolas, Merkler, Doron, Hugues, Stéphanie, Martinvalet, Denis, Manoury, Bénédicte, Demaurex, Nicolas
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701258/
https://ncbi.nlm.nih.gov/pubmed/29176619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01600-6
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