Can kinomics and proteomics bridge the gap between pediatric cancers and newly designed kinase inhibitors?

Por van der Sligte, Naomi E., Kampen, Kim R., de Bont, Eveline S. J. M.
Publicado no Cell Mol Life Sci (2015)

Survival Trends and Long-Term Toxicity in Pediatric Patients with Osteosarcoma

Por Hagleitner, Melanie M., de Bont, Eveline S. J. M., te Loo, D. Maroeska W. M.
Publicado em 2012

Paradoxical down-regulation of p16(INK4a) mRNA with advancing age in Acute Myeloid Leukemia

Por de Jonge, Hendrik J.M., Woolthuis, Carolien M., de Bont, Eveline S.J.M., Huls, Gerwin
Publicado em 2009

The Role of Intestinal Microbiota in the Development and Severity of Chemotherapy-Induced Mucositis

Por van Vliet, Michel J., Harmsen, Hermie J. M., de Bont, Eveline S. J. M., Tissing, Wim J. E.
Publicado em 2010

Malnutrition is associated with worse health-related quality of life in children with cancer

Por Brinksma, Aeltsje, Sanderman, Robbert, Roodbol, Petrie F., Sulkers, Esther, Burgerhof, Johannes G. M., de Bont, Eveline S. J. M., Tissing, Wim J. E.
Publicado no Support Care Cancer (2015)

Effect of IKZF1 deletions on signal transduction pathways in Philadelphia chromosome negative pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL)

Por van der Sligte, Naomi E, Scherpen, Frank J G, ter Elst, Arja, Guryev, Victor, van Leeuwen, Frank N, de Bont, Eveline S J M
Publicado no Exp Hematol Oncol (2015)

Epidermal growth factor receptor is expressed and active in a subset of acute myeloid leukemia

Por Mahmud, Hasan, Kornblau, Steven M., ter Elst, Arja, Scherpen, Frank J. G., Qiu, Yi Hua, Coombes, Kevin R., de Bont, Eveline S. J. M.
Publicado no J Hematol Oncol (2016)

Prognostic impact of white blood cell count in intermediate risk acute myeloid leukemia: relevance of mutated NPM1 and FLT3-ITD

Por de Jonge, Hendrik J.M., Valk, Peter J.M., de Bont, Eveline S.J.M., Schuringa, Jan Jacob, Ossenkoppele, Gert, Vellenga, Edo, Huls, Gerwin
Publicado em 2011

The diagnostic value of CRP, IL-8, PCT, and sTREM-1 in the detection of bacterial infections in pediatric oncology patients with febrile neutropenia

Por Miedema, Karin G. E., de Bont, Eveline S. J. M., Elferink, Rob F. M. Oude, van Vliet, Michel J., Nijhuis, Claudi S. M. Oude, Kamps, Willem A., Tissing, Wim J. E.
Publicado em 2010

High Acute Myeloid Leukemia derived VEGFA levels are associated with a specific vascular morphology in the leukemic bone marrow

Por Weidenaar, Alida C., ter Elst, Arja, Koopmans-Klein, Gineke, Rosati, Stefano, den Dunnen, Wilfred F. A., Meeuwsen-de Boer, Tiny, Kamps, Willem A., Vellenga, Edo, de Bont, Eveline S. J. M.
Publicado em 2011

Exogenous HGF Bypasses the Effects of ErbB Inhibition on Tumor Cell Viability in Medulloblastoma Cell Lines

Por Zomerman, Walderik W., Plasschaert, Sabine L. A., Diks, Sander H., Lourens, Harm-Jan, Meeuwsen-de Boer, Tiny, Hoving, Eelco W., den Dunnen, Wilfred F. A., de Bont, Eveline S. J. M.
Publicado no PLoS One (2015)

Growth-Factor-Driven Rescue to Receptor Tyrosine Kinase (RTK) Inhibitors through Akt and Erk Phosphorylation in Pediatric Low Grade Astrocytoma and Ependymoma

Por Sie, Mariska, den Dunnen, Wilfred F. A., Lourens, Harm Jan, Meeuwsen-de Boer, Tiny G. J., Scherpen, Frank J. G., Zomerman, Walderik W., Kampen, Kim R., Hoving, Eelco W., de Bont, Eveline S. J. M.
Publicado no PLoS One (2015)

Essential role for cyclic-AMP responsive element binding protein 1 (CREB) in the survival of acute lymphoblastic leukemia

Por van der Sligte, Naomi E., Kampen, Kim R., ter Elst, Arja, Scherpen, Frank J.G., Meeuwsen-de Boer, Tiny G.J., Guryev, Victor, van Leeuwen, Frank N., Kornblau, Steven M., de Bont, Eveline S.J.M.
Publicado no Oncotarget (2015)

Influence of Genetic Variants in TPMT and COMT Associated with Cisplatin Induced Hearing Loss in Patients with Cancer: Two New Cohorts and a Meta-Analysis Reveal Significant Hetero...

Por Hagleitner, Melanie M., Coenen, Marieke J. H., Patino-Garcia, Ana, de Bont, Eveline S. J. M., Gonzalez-Neira, Anna, Vos, Hanneke I., van Leeuwen, Frank N., Gelderblom, Hans, Hoogerbrugge, Peter M., Guchelaar, Henk-Jan, te Loo, Maroeska W. M.
Publicado no PLoS One (2014)

Gene Expression Profiles Associated with Pediatric Relapsed AML

Por Bachas, Costa, Schuurhuis, Gerrit Jan, Zwaan, C. Michel, van den Heuvel-Eibrink, Marry M., den Boer, Monique L., de Bont, Eveline S. J. M., Kwidama, Zinia J., Reinhardt, Dirk, Creutzig, Ursula, de Haas, Valérie, Kaspers, Gertjan J. L., Cloos, Jacqueline
Publicado no PLoS One (2015)

Evidence Based Selection of Housekeeping Genes

Por de Jonge, Hendrik J. M., Fehrmann, Rudolf S. N., de Bont, Eveline S. J. M., Hofstra, Robert M. W., Gerbens, Frans, Kamps, Willem A., de Vries, Elisabeth G. E., van der Zee, Ate G. J., te Meerman, Gerard J., ter Elst, Arja
Publicado em 2007

EphB2 activity plays a pivotal role in pediatric medulloblastoma cell adhesion and invasion

Por Sikkema, Arend H., den Dunnen, Wilfred F.A., Hulleman, Esther, van Vuurden, Dannis G., Garcia-Manero, Guillermo, Yang, Hui, Scherpen, Frank J.G., Kampen, Kim R., Hoving, Eelco W., Kamps, Willem A., Diks, Sander H., Peppelenbosch, Maikel P., de Bont, Eveline S.J.M.
Publicado em 2012

Single-cell sequencing reveals karyotype heterogeneity in murine and human malignancies

Por Bakker, Bjorn, Taudt, Aaron, Belderbos, Mirjam E., Porubsky, David, Spierings, Diana C. J., de Jong, Tristan V., Halsema, Nancy, Kazemier, Hinke G., Hoekstra-Wakker, Karina, Bradley, Allan, de Bont, Eveline S. J. M., van den Berg, Anke, Guryev, Victor, Lansdorp, Peter M., Colomé-Tatché, Maria, Foijer, Floris
Publicado no Genome Biol (2016)

A New Perspective on Transcriptional System Regulation (TSR): Towards TSR Profiling

Por Fehrmann, Rudolf S. N., de Jonge, Hendrik J. M., ter Elst, Arja, de Vries, André, Crijns, Anne G. P., Weidenaar, Alida C., Gerbens, Frans, de Jong, Steven, van der Zee, Ate G. J., de Vries, Elisabeth G. E., Kamps, Willem A., Hofstra, Robert M. W., te Meerman, Gerard J., de Bont, Eveline S. J. M.
Publicado em 2008

Characterization of CEBPA mutations and promoter hypermethylation in pediatric acute myeloid leukemia

Por Hollink, Iris H.I.M., van den Heuvel-Eibrink, Marry M., Arentsen-Peters, Susan T.C.J.M., Zimmermann, Martin, Peeters, Justine K., Valk, Peter J.M., Balgobind, Brian V., Sonneveld, Edwin, Kaspers, Gertjan J.L., de Bont, Eveline S.J.M., Trka, Jan, Baruchel, Andre, Creutzig, Ursula, Pieters, Rob, Reinhardt, Dirk, Zwaan, C. Michel
Publicado em 2011