Effects of hypoxia on anabolic and catabolic gene expression and DNA methylation in OA chondrocytes

Por Alvarez, Karl, de Andrés, María C, Takahashi, Atsushi, Oreffo, Richard O C
Publicado no BMC Musculoskelet Disord (2014)

The Potential of microRNAs for Stem Cell-based Therapy for Degenerative Skeletal Diseases

Por Budd, Emma, Waddell, Shona, de Andrés, María C., Oreffo, Richard O. C.
Publicado no Curr Mol Biol Rep (2017)

MiR-146b is down-regulated during the chondrogenic differentiation of human bone marrow derived skeletal stem cells and up-regulated in osteoarthritis

Por Budd, Emma, de Andrés, María C., Sanchez-Elsner, Tilman, Oreffo, Richard O. C.
Publicado no Sci Rep (2017)

Hsp90β inhibition modulates nitric oxide production and nitric oxide-induced apoptosis in human chondrocytes

Por Calamia, Valentina, de Andrés, Maria C, Oreiro, Natividad, Ruiz-Romero, Cristina, Blanco, Francisco J
Publicado em 2011

Nitric oxide compounds have different effects profiles on human articular chondrocyte metabolism

Por de Andrés, María C, Maneiro, Emilia, Martín, Miguel A, Arenas, Joaquín, Blanco, Francisco J
Publicado em 2013

Size and dielectric properties of skeletal stem cells change critically after enrichment and expansion from human bone marrow: consequences for microfluidic cell sorting

Por Xavier, Miguel, de Andrés, María C., Spencer, Daniel, Oreffo, Richard O. C., Morgan, Hywel
Publicado no J R Soc Interface (2017)

DNA methylation of the RUNX2 P1 promoter mediates MMP13 transcription in chondrocytes

Por Takahashi, Atsushi, de Andrés, María C., Hashimoto, Ko, Itoi, Eiji, Otero, Miguel, Goldring, Mary B., Oreffo, Richard O. C.
Publicado no Sci Rep (2017)

Epigenetic Regulation during Fetal Femur Development: DNA Methylation Matters

Por de Andrés, María C., Kingham, Emmajayne, Imagawa, Kei, Gonzalez, Antonio, Roach, Helmtrud I., Wilson, David I., Oreffo, Richard O. C.
Publicado em 2013

Suppressors of cytokine signalling (SOCS) are reduced in osteoarthritis

Por de Andrés, María C., Imagawa, Kei, Hashimoto, Ko, Gonzalez, Antonio, Goldring, Mary B., Roach, Helmtrud I., Oreffo, Richard O.C.
Publicado em 2011

Loss of Methylation in CpG Sites in the NF-κB Enhancer Elements of Inducible Nitric Oxide Synthase Is Responsible for Gene Induction in Human Articular Chondrocytes

Por de Andrés, María C., Imagawa, Kei, Hashimoto, Ko, Gonzalez, Antonio, Roach, Helmtrud I., Goldring, Mary B., Oreffo, Richard O. C.
Publicado em 2013

Assessment of global DNA methylation in peripheral blood cell subpopulations of early rheumatoid arthritis before and after methotrexate

Por de Andres, María C., Perez-Pampin, Eva, Calaza, Manuel, Santaclara, Francisco J., Ortea, Ignacio, Gomez-Reino, Juan J., Gonzalez, Antonio
Publicado no Arthritis Res Ther (2015)

Association of Reduced Type IX Collagen Gene Expression in Human Osteoarthritic Chondrocytes With Epigenetic Silencing by DNA Hypermethylation

Por Imagawa, Kei, de Andrés, María C, Hashimoto, Ko, Itoi, Eiji, Otero, Miguel, Roach, Helmtrud I, Goldring, Mary B, Oreffo, Richard O C
Publicado em 2014

Regulated Transcription of Human Matrix Metalloproteinase 13 (MMP13) and Interleukin-1β (IL1B) Genes in Chondrocytes Depends on Methylation of Specific Proximal Promoter CpG Sites

Por Hashimoto, Ko, Otero, Miguel, Imagawa, Kei, de Andrés, María C., Coico, Jonathan M., Roach, Helmtrud I., Oreffo, Richard O. C., Marcu, Kenneth B., Goldring, Mary B.
Publicado em 2013

Nanotopography controls cell cycle changes involved with skeletal stem cell self-renewal and multipotency

Por Lee, Louisa C.Y., Gadegaard, Nikolaj, de Andrés, María C., Turner, Lesley-Anne, Burgess, Karl V., Yarwood, Stephen J., Wells, Julia, Salmeron-Sanchez, Manuel, Meek, Dominic, Oreffo, Richard O.C., Dalby, Matthew J.
Publicado no Biomaterials (2017)