Altered Amyloid-β Metabolism and Deposition in Genomic-based β-Secretase Transgenic Mice

由 Chiocco, Matthew J., Kulnane, Laura Shapiro, Younkin, Linda, Younkin, Steve, Evin, Geneviève, Lamb, Bruce T.
出版 2004

Age-Dependent Changes in Brain, CSF, and Plasma Amyloid β Protein in the Tg2576 Transgenic Mouse Model of Alzheimer's Disease

由 Kawarabayashi, Takeshi, Younkin, Linda H., Saido, Takaomi C., Shoji, Mikio, Ashe, Karen Hsiao, Younkin, Steven G.
發表在 J Neurosci (2001)

Reversible Memory Loss in a Mouse Transgenic Model of Alzheimer's Disease

由 Kotilinek, Linda A., Bacskai, Brian, Westerman, Marcus, Kawarabayashi, Takeshi, Younkin, Linda, Hyman, Bradley T., Younkin, Steven, Ashe, Karen H.
發表在 J Neurosci (2002)

Aβ1–40-related reduction in functional hyperemia in mouse neocortex during somatosensory activation

由 Niwa, Kiyoshi, Younkin, Linda, Ebeling, Christine, Turner, Sherry K., Westaway, David, Younkin, Steven, Ashe, Karen Hsiao, Carlson, George A., Iadecola, Costantino
出版 2000

Rodent Aβ Modulates the Solubility and Distribution of Amyloid Deposits in Transgenic Mice()

由 Jankowsky, Joanna L., Younkin, Linda H., Gonzales, Victoria, Fadale, Daniel J., Slunt, Hilda H., Lester, Henry A., Younkin, Steven G., Borchelt, David R.
發表在 J Biol Chem (2007)

Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein

由 Park, Laibaik, Zhou, Ping, Pitstick, Rose, Capone, Carmen, Anrather, Josef, Norris, Erin H., Younkin, Linda, Younkin, Steven, Carlson, George, McEwen, Bruce S., Iadecola, Costantino
出版 2008

Tau Loss Attenuates Neuronal Network Hyperexcitability in Mouse and Drosophila Genetic Models of Epilepsy

由 Holth, Jerrah K., Bomben, Valerie C., Reed, J. Graham, Inoue, Taeko, Younkin, Linda, Younkin, Steven G., Pautler, Robia G., Botas, Juan, Noebels, Jeffrey L.
出版 2013

The Relationship between Aβ and Memory in the Tg2576 Mouse Model of Alzheimer's Disease

由 Westerman, Marcus A., Cooper-Blacketer, Deirdre, Mariash, Ami, Kotilinek, Linda, Kawarabayashi, Takeshi, Younkin, Linda H., Carlson, George A., Younkin, Steven G., Ashe, Karen H.
發表在 J Neurosci (2002)

Brain Perivascular Macrophages Initiate the Neurovascular Dysfunction of Alzheimer Aβ Peptides

由 Park, Laibaik, Uekawa, Ken, Bonilla, Lidia Garcia, Koizumi, Kenzo, Murphy, Michelle, Pistik, Rose, Younkin, Linda, Younkin, Steven, Zhou, Ping, Carlson, George, Anrather, Josef, Iadecola, Costantino
發表在 Circ Res (2017)

Dimeric Amyloid β Protein Rapidly Accumulates in Lipid Rafts followed by Apolipoprotein E and Phosphorylated Tau Accumulation in the Tg2576 Mouse Model of Alzheimer's Disease

由 Kawarabayashi, Takeshi, Shoji, Mikio, Younkin, Linda H., Wen-Lang, Lin, Dickson, Dennis W., Murakami, Tetsuro, Matsubara, Etsuro, Abe, Koji, Ashe, Karen Hsiao, Younkin, Steven G.
發表在 J Neurosci (2004)

Environmental Enrichment Mitigates Cognitive Deficits in a Mouse Model of Alzheimer's Disease

由 Jankowsky, Joanna L., Melnikova, Tatiana, Fadale, Daniel J., Xu, Guilian M., Slunt, Hilda H., Gonzales, Victoria, Younkin, Linda H., Younkin, Steven G., Borchelt, David R., Savonenko, Alena V.
發表在 J Neurosci (2005)

Association of Plasma Beta-Amyloid Level and Cognitive Reserve with Subsequent Cognitive Decline

由 Yaffe, Kristine, Weston, Andrea, Graff-Radford, Neill R., Satterfield, Suzanne, Simonsick, Eleanor M., Younkin, Steven G., Younkin, Linda H., Kuller, Lewis, Ayonayon, Hilsa N., Ding, Jingzhong, Harris, Tamara B.
出版 2011

Plasma amyloid β and risk of Alzheimer’s disease in the Framingham Heart Study

由 Chouraki, Vincent, Beiser, Alexa, Younkin, Linda, Preis, Sarah Rosner, Weinstein, Galit, Hansson, Oskar, Skoog, Ingmar, Lambert, Jean-Charles, Au, Rhoda, Launer, Lenore, Wolf, Philip A, Younkin, Steven, Seshadri, Sudha
發表在 Alzheimers Dement (2014)

Innate immunity receptor CD36 promotes cerebral amyloid angiopathy

由 Park, Laibaik, Zhou, Joan, Zhou, Ping, Pistick, Rose, El Jamal, Sleiman, Younkin, Linda, Pierce, Joseph, Arreguin, Andrea, Anrather, Josef, Younkin, Steven G., Carlson, George A., McEwen, Bruce S., Iadecola, Costantino
出版 2013

Scavenger receptor CD36 is essential for the cerebrovascular oxidative stress and neurovascular dysfunction induced by amyloid-β

由 Park, Laibaik, Wang, Gang, Zhou, Ping, Zhou, Joan, Pitstick, Rose, Previti, Mary Lou, Younkin, Linda, Younkin, Steven G., Van Nostrand, William E., Cho, Sunghee, Anrather, Josef, Carlson, George A., Iadecola, Costantino
出版 2011

Persistent Amyloidosis following Suppression of Aβ Production in a Transgenic Model of Alzheimer Disease

由 Jankowsky, Joanna L, Slunt, Hilda H, Gonzales, Victoria, Savonenko, Alena V, Wen, Jason C, Jenkins, Nancy A, Copeland, Neal G, Younkin, Linda H, Lester, Henry A, Younkin, Steven G, Borchelt, David R
出版 2005

Involvement of β-site APP cleaving enzyme 1 (BACE1) in amyloid precursor protein-mediated enhancement of memory and activity-dependent synaptic plasticity

由 Ma, Huifang, Lesné, Sylvain, Kotilinek, Linda, Steidl-Nichols, Jill V., Sherman, Mathew, Younkin, Linda, Younkin, Steven, Forster, Colleen, Sergeant, Nicolas, Delacourte, André, Vassar, Robert, Citron, Martin, Kofuji, Paulo, Boland, Linda M., Ashe, Karen H.
出版 2007

Fine mapping of the α-T catenin gene to a quantitative trait locus on chromosome 10 in late-onset Alzheimer’s disease pedigrees

由 Ertekin-Taner, Nilüfer, Ronald, James, Asahara, Hideaki, Younkin, Linda, Hella, Maria, Jain, Shushant, Gnida, Eugene, Younkin, Samuel, Fadale, Daniel, Ohyagi, Yasumasa, Singleton, Adam, Scanlin, Leah, de Andrade, Mariza, Petersen, Ronald, Graff-Radford, Neill, Hutton, Michael, Younkin, Steven
出版 2003

Cyclooxygenase-2 inhibition improves amyloid-β-mediated suppression of memory and synaptic plasticity

由 Kotilinek, Linda A., Westerman, Marcus A., Wang, Qinwen, Panizzon, Kimberly, Lim, Giselle P., Simonyi, Agnes, Lesne, Sylvain, Falinska, Agnieszka, Younkin, Linda H., Younkin, Steven G., Rowan, Michael, Cleary, James, Wallis, Roi Ann, Sun, GraceY., Cole, Greg, Frautschy, Sally, Anwyl, Roger, Ashe, Karen H.
出版 2008

Genetically-controlled Vesicle-Associated Membrane Protein 1 expression may contribute to Alzheimer’s pathophysiology and susceptibility

由 Sevlever, Daniel, Zou, Fanggeng, Ma, Li, Carrasquillo, Sebastian, Crump, Michael G, Culley, Oliver J, Hunter, Talisha A, Bisceglio, Gina D, Younkin, Linda, Allen, Mariet, Carrasquillo, Minerva M, Sando, Sigrid B, Aasly, Jan O, Dickson, Dennis W, Graff-Radford, Neill R, Petersen, Ronald C, Belbin, Olivia
發表在 Mol Neurodegener (2015)