Altered Amyloid-β Metabolism and Deposition in Genomic-based β-Secretase Transgenic Mice

по Chiocco, Matthew J., Kulnane, Laura Shapiro, Younkin, Linda, Younkin, Steve, Evin, Geneviève, Lamb, Bruce T.
Опубликовано 2004

Age-Dependent Changes in Brain, CSF, and Plasma Amyloid β Protein in the Tg2576 Transgenic Mouse Model of Alzheimer's Disease

по Kawarabayashi, Takeshi, Younkin, Linda H., Saido, Takaomi C., Shoji, Mikio, Ashe, Karen Hsiao, Younkin, Steven G.
Опубликовано в: J Neurosci (2001)

Reversible Memory Loss in a Mouse Transgenic Model of Alzheimer's Disease

по Kotilinek, Linda A., Bacskai, Brian, Westerman, Marcus, Kawarabayashi, Takeshi, Younkin, Linda, Hyman, Bradley T., Younkin, Steven, Ashe, Karen H.
Опубликовано в: J Neurosci (2002)

Aβ1–40-related reduction in functional hyperemia in mouse neocortex during somatosensory activation

по Niwa, Kiyoshi, Younkin, Linda, Ebeling, Christine, Turner, Sherry K., Westaway, David, Younkin, Steven, Ashe, Karen Hsiao, Carlson, George A., Iadecola, Costantino
Опубликовано 2000

Rodent Aβ Modulates the Solubility and Distribution of Amyloid Deposits in Transgenic Mice()

по Jankowsky, Joanna L., Younkin, Linda H., Gonzales, Victoria, Fadale, Daniel J., Slunt, Hilda H., Lester, Henry A., Younkin, Steven G., Borchelt, David R.
Опубликовано в: J Biol Chem (2007)

Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein

по Park, Laibaik, Zhou, Ping, Pitstick, Rose, Capone, Carmen, Anrather, Josef, Norris, Erin H., Younkin, Linda, Younkin, Steven, Carlson, George, McEwen, Bruce S., Iadecola, Costantino
Опубликовано 2008

Tau Loss Attenuates Neuronal Network Hyperexcitability in Mouse and Drosophila Genetic Models of Epilepsy

по Holth, Jerrah K., Bomben, Valerie C., Reed, J. Graham, Inoue, Taeko, Younkin, Linda, Younkin, Steven G., Pautler, Robia G., Botas, Juan, Noebels, Jeffrey L.
Опубликовано 2013

The Relationship between Aβ and Memory in the Tg2576 Mouse Model of Alzheimer's Disease

по Westerman, Marcus A., Cooper-Blacketer, Deirdre, Mariash, Ami, Kotilinek, Linda, Kawarabayashi, Takeshi, Younkin, Linda H., Carlson, George A., Younkin, Steven G., Ashe, Karen H.
Опубликовано в: J Neurosci (2002)

Brain Perivascular Macrophages Initiate the Neurovascular Dysfunction of Alzheimer Aβ Peptides

по Park, Laibaik, Uekawa, Ken, Bonilla, Lidia Garcia, Koizumi, Kenzo, Murphy, Michelle, Pistik, Rose, Younkin, Linda, Younkin, Steven, Zhou, Ping, Carlson, George, Anrather, Josef, Iadecola, Costantino
Опубликовано в: Circ Res (2017)

Dimeric Amyloid β Protein Rapidly Accumulates in Lipid Rafts followed by Apolipoprotein E and Phosphorylated Tau Accumulation in the Tg2576 Mouse Model of Alzheimer's Disease

по Kawarabayashi, Takeshi, Shoji, Mikio, Younkin, Linda H., Wen-Lang, Lin, Dickson, Dennis W., Murakami, Tetsuro, Matsubara, Etsuro, Abe, Koji, Ashe, Karen Hsiao, Younkin, Steven G.
Опубликовано в: J Neurosci (2004)

Environmental Enrichment Mitigates Cognitive Deficits in a Mouse Model of Alzheimer's Disease

по Jankowsky, Joanna L., Melnikova, Tatiana, Fadale, Daniel J., Xu, Guilian M., Slunt, Hilda H., Gonzales, Victoria, Younkin, Linda H., Younkin, Steven G., Borchelt, David R., Savonenko, Alena V.
Опубликовано в: J Neurosci (2005)

Association of Plasma Beta-Amyloid Level and Cognitive Reserve with Subsequent Cognitive Decline

по Yaffe, Kristine, Weston, Andrea, Graff-Radford, Neill R., Satterfield, Suzanne, Simonsick, Eleanor M., Younkin, Steven G., Younkin, Linda H., Kuller, Lewis, Ayonayon, Hilsa N., Ding, Jingzhong, Harris, Tamara B.
Опубликовано 2011

Plasma amyloid β and risk of Alzheimer’s disease in the Framingham Heart Study

по Chouraki, Vincent, Beiser, Alexa, Younkin, Linda, Preis, Sarah Rosner, Weinstein, Galit, Hansson, Oskar, Skoog, Ingmar, Lambert, Jean-Charles, Au, Rhoda, Launer, Lenore, Wolf, Philip A, Younkin, Steven, Seshadri, Sudha
Опубликовано в: Alzheimers Dement (2014)

Innate immunity receptor CD36 promotes cerebral amyloid angiopathy

по Park, Laibaik, Zhou, Joan, Zhou, Ping, Pistick, Rose, El Jamal, Sleiman, Younkin, Linda, Pierce, Joseph, Arreguin, Andrea, Anrather, Josef, Younkin, Steven G., Carlson, George A., McEwen, Bruce S., Iadecola, Costantino
Опубликовано 2013

Scavenger receptor CD36 is essential for the cerebrovascular oxidative stress and neurovascular dysfunction induced by amyloid-β

по Park, Laibaik, Wang, Gang, Zhou, Ping, Zhou, Joan, Pitstick, Rose, Previti, Mary Lou, Younkin, Linda, Younkin, Steven G., Van Nostrand, William E., Cho, Sunghee, Anrather, Josef, Carlson, George A., Iadecola, Costantino
Опубликовано 2011

Persistent Amyloidosis following Suppression of Aβ Production in a Transgenic Model of Alzheimer Disease

по Jankowsky, Joanna L, Slunt, Hilda H, Gonzales, Victoria, Savonenko, Alena V, Wen, Jason C, Jenkins, Nancy A, Copeland, Neal G, Younkin, Linda H, Lester, Henry A, Younkin, Steven G, Borchelt, David R
Опубликовано 2005

Involvement of β-site APP cleaving enzyme 1 (BACE1) in amyloid precursor protein-mediated enhancement of memory and activity-dependent synaptic plasticity

по Ma, Huifang, Lesné, Sylvain, Kotilinek, Linda, Steidl-Nichols, Jill V., Sherman, Mathew, Younkin, Linda, Younkin, Steven, Forster, Colleen, Sergeant, Nicolas, Delacourte, André, Vassar, Robert, Citron, Martin, Kofuji, Paulo, Boland, Linda M., Ashe, Karen H.
Опубликовано 2007

Fine mapping of the α-T catenin gene to a quantitative trait locus on chromosome 10 in late-onset Alzheimer’s disease pedigrees

по Ertekin-Taner, Nilüfer, Ronald, James, Asahara, Hideaki, Younkin, Linda, Hella, Maria, Jain, Shushant, Gnida, Eugene, Younkin, Samuel, Fadale, Daniel, Ohyagi, Yasumasa, Singleton, Adam, Scanlin, Leah, de Andrade, Mariza, Petersen, Ronald, Graff-Radford, Neill, Hutton, Michael, Younkin, Steven
Опубликовано 2003

Cyclooxygenase-2 inhibition improves amyloid-β-mediated suppression of memory and synaptic plasticity

по Kotilinek, Linda A., Westerman, Marcus A., Wang, Qinwen, Panizzon, Kimberly, Lim, Giselle P., Simonyi, Agnes, Lesne, Sylvain, Falinska, Agnieszka, Younkin, Linda H., Younkin, Steven G., Rowan, Michael, Cleary, James, Wallis, Roi Ann, Sun, GraceY., Cole, Greg, Frautschy, Sally, Anwyl, Roger, Ashe, Karen H.
Опубликовано 2008

Genetically-controlled Vesicle-Associated Membrane Protein 1 expression may contribute to Alzheimer’s pathophysiology and susceptibility

по Sevlever, Daniel, Zou, Fanggeng, Ma, Li, Carrasquillo, Sebastian, Crump, Michael G, Culley, Oliver J, Hunter, Talisha A, Bisceglio, Gina D, Younkin, Linda, Allen, Mariet, Carrasquillo, Minerva M, Sando, Sigrid B, Aasly, Jan O, Dickson, Dennis W, Graff-Radford, Neill R, Petersen, Ronald C, Belbin, Olivia
Опубликовано в: Mol Neurodegener (2015)