Altered Amyloid-β Metabolism and Deposition in Genomic-based β-Secretase Transgenic Mice

著者: Chiocco, Matthew J., Kulnane, Laura Shapiro, Younkin, Linda, Younkin, Steve, Evin, Geneviève, Lamb, Bruce T.
出版事項 2004

Age-Dependent Changes in Brain, CSF, and Plasma Amyloid β Protein in the Tg2576 Transgenic Mouse Model of Alzheimer's Disease

著者: Kawarabayashi, Takeshi, Younkin, Linda H., Saido, Takaomi C., Shoji, Mikio, Ashe, Karen Hsiao, Younkin, Steven G.
出版年 J Neurosci (2001)

Reversible Memory Loss in a Mouse Transgenic Model of Alzheimer's Disease

著者: Kotilinek, Linda A., Bacskai, Brian, Westerman, Marcus, Kawarabayashi, Takeshi, Younkin, Linda, Hyman, Bradley T., Younkin, Steven, Ashe, Karen H.
出版年 J Neurosci (2002)

Aβ1–40-related reduction in functional hyperemia in mouse neocortex during somatosensory activation

著者: Niwa, Kiyoshi, Younkin, Linda, Ebeling, Christine, Turner, Sherry K., Westaway, David, Younkin, Steven, Ashe, Karen Hsiao, Carlson, George A., Iadecola, Costantino
出版事項 2000

Rodent Aβ Modulates the Solubility and Distribution of Amyloid Deposits in Transgenic Mice()

著者: Jankowsky, Joanna L., Younkin, Linda H., Gonzales, Victoria, Fadale, Daniel J., Slunt, Hilda H., Lester, Henry A., Younkin, Steven G., Borchelt, David R.
出版年 J Biol Chem (2007)

Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein

著者: Park, Laibaik, Zhou, Ping, Pitstick, Rose, Capone, Carmen, Anrather, Josef, Norris, Erin H., Younkin, Linda, Younkin, Steven, Carlson, George, McEwen, Bruce S., Iadecola, Costantino
出版事項 2008

Tau Loss Attenuates Neuronal Network Hyperexcitability in Mouse and Drosophila Genetic Models of Epilepsy

著者: Holth, Jerrah K., Bomben, Valerie C., Reed, J. Graham, Inoue, Taeko, Younkin, Linda, Younkin, Steven G., Pautler, Robia G., Botas, Juan, Noebels, Jeffrey L.
出版事項 2013

The Relationship between Aβ and Memory in the Tg2576 Mouse Model of Alzheimer's Disease

著者: Westerman, Marcus A., Cooper-Blacketer, Deirdre, Mariash, Ami, Kotilinek, Linda, Kawarabayashi, Takeshi, Younkin, Linda H., Carlson, George A., Younkin, Steven G., Ashe, Karen H.
出版年 J Neurosci (2002)

Brain Perivascular Macrophages Initiate the Neurovascular Dysfunction of Alzheimer Aβ Peptides

著者: Park, Laibaik, Uekawa, Ken, Bonilla, Lidia Garcia, Koizumi, Kenzo, Murphy, Michelle, Pistik, Rose, Younkin, Linda, Younkin, Steven, Zhou, Ping, Carlson, George, Anrather, Josef, Iadecola, Costantino
出版年 Circ Res (2017)

Dimeric Amyloid β Protein Rapidly Accumulates in Lipid Rafts followed by Apolipoprotein E and Phosphorylated Tau Accumulation in the Tg2576 Mouse Model of Alzheimer's Disease

著者: Kawarabayashi, Takeshi, Shoji, Mikio, Younkin, Linda H., Wen-Lang, Lin, Dickson, Dennis W., Murakami, Tetsuro, Matsubara, Etsuro, Abe, Koji, Ashe, Karen Hsiao, Younkin, Steven G.
出版年 J Neurosci (2004)

Environmental Enrichment Mitigates Cognitive Deficits in a Mouse Model of Alzheimer's Disease

著者: Jankowsky, Joanna L., Melnikova, Tatiana, Fadale, Daniel J., Xu, Guilian M., Slunt, Hilda H., Gonzales, Victoria, Younkin, Linda H., Younkin, Steven G., Borchelt, David R., Savonenko, Alena V.
出版年 J Neurosci (2005)

Association of Plasma Beta-Amyloid Level and Cognitive Reserve with Subsequent Cognitive Decline

著者: Yaffe, Kristine, Weston, Andrea, Graff-Radford, Neill R., Satterfield, Suzanne, Simonsick, Eleanor M., Younkin, Steven G., Younkin, Linda H., Kuller, Lewis, Ayonayon, Hilsa N., Ding, Jingzhong, Harris, Tamara B.
出版事項 2011

Plasma amyloid β and risk of Alzheimer’s disease in the Framingham Heart Study

著者: Chouraki, Vincent, Beiser, Alexa, Younkin, Linda, Preis, Sarah Rosner, Weinstein, Galit, Hansson, Oskar, Skoog, Ingmar, Lambert, Jean-Charles, Au, Rhoda, Launer, Lenore, Wolf, Philip A, Younkin, Steven, Seshadri, Sudha
出版年 Alzheimers Dement (2014)

Innate immunity receptor CD36 promotes cerebral amyloid angiopathy

著者: Park, Laibaik, Zhou, Joan, Zhou, Ping, Pistick, Rose, El Jamal, Sleiman, Younkin, Linda, Pierce, Joseph, Arreguin, Andrea, Anrather, Josef, Younkin, Steven G., Carlson, George A., McEwen, Bruce S., Iadecola, Costantino
出版事項 2013

Scavenger receptor CD36 is essential for the cerebrovascular oxidative stress and neurovascular dysfunction induced by amyloid-β

著者: Park, Laibaik, Wang, Gang, Zhou, Ping, Zhou, Joan, Pitstick, Rose, Previti, Mary Lou, Younkin, Linda, Younkin, Steven G., Van Nostrand, William E., Cho, Sunghee, Anrather, Josef, Carlson, George A., Iadecola, Costantino
出版事項 2011

Persistent Amyloidosis following Suppression of Aβ Production in a Transgenic Model of Alzheimer Disease

著者: Jankowsky, Joanna L, Slunt, Hilda H, Gonzales, Victoria, Savonenko, Alena V, Wen, Jason C, Jenkins, Nancy A, Copeland, Neal G, Younkin, Linda H, Lester, Henry A, Younkin, Steven G, Borchelt, David R
出版事項 2005

Involvement of β-site APP cleaving enzyme 1 (BACE1) in amyloid precursor protein-mediated enhancement of memory and activity-dependent synaptic plasticity

著者: Ma, Huifang, Lesné, Sylvain, Kotilinek, Linda, Steidl-Nichols, Jill V., Sherman, Mathew, Younkin, Linda, Younkin, Steven, Forster, Colleen, Sergeant, Nicolas, Delacourte, André, Vassar, Robert, Citron, Martin, Kofuji, Paulo, Boland, Linda M., Ashe, Karen H.
出版事項 2007

Fine mapping of the α-T catenin gene to a quantitative trait locus on chromosome 10 in late-onset Alzheimer’s disease pedigrees

著者: Ertekin-Taner, Nilüfer, Ronald, James, Asahara, Hideaki, Younkin, Linda, Hella, Maria, Jain, Shushant, Gnida, Eugene, Younkin, Samuel, Fadale, Daniel, Ohyagi, Yasumasa, Singleton, Adam, Scanlin, Leah, de Andrade, Mariza, Petersen, Ronald, Graff-Radford, Neill, Hutton, Michael, Younkin, Steven
出版事項 2003

Cyclooxygenase-2 inhibition improves amyloid-β-mediated suppression of memory and synaptic plasticity

著者: Kotilinek, Linda A., Westerman, Marcus A., Wang, Qinwen, Panizzon, Kimberly, Lim, Giselle P., Simonyi, Agnes, Lesne, Sylvain, Falinska, Agnieszka, Younkin, Linda H., Younkin, Steven G., Rowan, Michael, Cleary, James, Wallis, Roi Ann, Sun, GraceY., Cole, Greg, Frautschy, Sally, Anwyl, Roger, Ashe, Karen H.
出版事項 2008

Genetically-controlled Vesicle-Associated Membrane Protein 1 expression may contribute to Alzheimer’s pathophysiology and susceptibility

著者: Sevlever, Daniel, Zou, Fanggeng, Ma, Li, Carrasquillo, Sebastian, Crump, Michael G, Culley, Oliver J, Hunter, Talisha A, Bisceglio, Gina D, Younkin, Linda, Allen, Mariet, Carrasquillo, Minerva M, Sando, Sigrid B, Aasly, Jan O, Dickson, Dennis W, Graff-Radford, Neill R, Petersen, Ronald C, Belbin, Olivia
出版年 Mol Neurodegener (2015)