Altered Amyloid-β Metabolism and Deposition in Genomic-based β-Secretase Transgenic Mice

gan Chiocco, Matthew J., Kulnane, Laura Shapiro, Younkin, Linda, Younkin, Steve, Evin, Geneviève, Lamb, Bruce T.
Cyhoeddwyd 2004

Age-Dependent Changes in Brain, CSF, and Plasma Amyloid β Protein in the Tg2576 Transgenic Mouse Model of Alzheimer's Disease

gan Kawarabayashi, Takeshi, Younkin, Linda H., Saido, Takaomi C., Shoji, Mikio, Ashe, Karen Hsiao, Younkin, Steven G.
Cyhoeddwyd yn J Neurosci (2001)

Reversible Memory Loss in a Mouse Transgenic Model of Alzheimer's Disease

gan Kotilinek, Linda A., Bacskai, Brian, Westerman, Marcus, Kawarabayashi, Takeshi, Younkin, Linda, Hyman, Bradley T., Younkin, Steven, Ashe, Karen H.
Cyhoeddwyd yn J Neurosci (2002)

Aβ1–40-related reduction in functional hyperemia in mouse neocortex during somatosensory activation

gan Niwa, Kiyoshi, Younkin, Linda, Ebeling, Christine, Turner, Sherry K., Westaway, David, Younkin, Steven, Ashe, Karen Hsiao, Carlson, George A., Iadecola, Costantino
Cyhoeddwyd 2000

Rodent Aβ Modulates the Solubility and Distribution of Amyloid Deposits in Transgenic Mice()

gan Jankowsky, Joanna L., Younkin, Linda H., Gonzales, Victoria, Fadale, Daniel J., Slunt, Hilda H., Lester, Henry A., Younkin, Steven G., Borchelt, David R.
Cyhoeddwyd yn J Biol Chem (2007)

Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein

gan Park, Laibaik, Zhou, Ping, Pitstick, Rose, Capone, Carmen, Anrather, Josef, Norris, Erin H., Younkin, Linda, Younkin, Steven, Carlson, George, McEwen, Bruce S., Iadecola, Costantino
Cyhoeddwyd 2008

Tau Loss Attenuates Neuronal Network Hyperexcitability in Mouse and Drosophila Genetic Models of Epilepsy

gan Holth, Jerrah K., Bomben, Valerie C., Reed, J. Graham, Inoue, Taeko, Younkin, Linda, Younkin, Steven G., Pautler, Robia G., Botas, Juan, Noebels, Jeffrey L.
Cyhoeddwyd 2013

The Relationship between Aβ and Memory in the Tg2576 Mouse Model of Alzheimer's Disease

gan Westerman, Marcus A., Cooper-Blacketer, Deirdre, Mariash, Ami, Kotilinek, Linda, Kawarabayashi, Takeshi, Younkin, Linda H., Carlson, George A., Younkin, Steven G., Ashe, Karen H.
Cyhoeddwyd yn J Neurosci (2002)

Brain Perivascular Macrophages Initiate the Neurovascular Dysfunction of Alzheimer Aβ Peptides

gan Park, Laibaik, Uekawa, Ken, Bonilla, Lidia Garcia, Koizumi, Kenzo, Murphy, Michelle, Pistik, Rose, Younkin, Linda, Younkin, Steven, Zhou, Ping, Carlson, George, Anrather, Josef, Iadecola, Costantino
Cyhoeddwyd yn Circ Res (2017)

Dimeric Amyloid β Protein Rapidly Accumulates in Lipid Rafts followed by Apolipoprotein E and Phosphorylated Tau Accumulation in the Tg2576 Mouse Model of Alzheimer's Disease

gan Kawarabayashi, Takeshi, Shoji, Mikio, Younkin, Linda H., Wen-Lang, Lin, Dickson, Dennis W., Murakami, Tetsuro, Matsubara, Etsuro, Abe, Koji, Ashe, Karen Hsiao, Younkin, Steven G.
Cyhoeddwyd yn J Neurosci (2004)

Environmental Enrichment Mitigates Cognitive Deficits in a Mouse Model of Alzheimer's Disease

gan Jankowsky, Joanna L., Melnikova, Tatiana, Fadale, Daniel J., Xu, Guilian M., Slunt, Hilda H., Gonzales, Victoria, Younkin, Linda H., Younkin, Steven G., Borchelt, David R., Savonenko, Alena V.
Cyhoeddwyd yn J Neurosci (2005)

Association of Plasma Beta-Amyloid Level and Cognitive Reserve with Subsequent Cognitive Decline

gan Yaffe, Kristine, Weston, Andrea, Graff-Radford, Neill R., Satterfield, Suzanne, Simonsick, Eleanor M., Younkin, Steven G., Younkin, Linda H., Kuller, Lewis, Ayonayon, Hilsa N., Ding, Jingzhong, Harris, Tamara B.
Cyhoeddwyd 2011

Plasma amyloid β and risk of Alzheimer’s disease in the Framingham Heart Study

gan Chouraki, Vincent, Beiser, Alexa, Younkin, Linda, Preis, Sarah Rosner, Weinstein, Galit, Hansson, Oskar, Skoog, Ingmar, Lambert, Jean-Charles, Au, Rhoda, Launer, Lenore, Wolf, Philip A, Younkin, Steven, Seshadri, Sudha
Cyhoeddwyd yn Alzheimers Dement (2014)

Innate immunity receptor CD36 promotes cerebral amyloid angiopathy

gan Park, Laibaik, Zhou, Joan, Zhou, Ping, Pistick, Rose, El Jamal, Sleiman, Younkin, Linda, Pierce, Joseph, Arreguin, Andrea, Anrather, Josef, Younkin, Steven G., Carlson, George A., McEwen, Bruce S., Iadecola, Costantino
Cyhoeddwyd 2013

Scavenger receptor CD36 is essential for the cerebrovascular oxidative stress and neurovascular dysfunction induced by amyloid-β

gan Park, Laibaik, Wang, Gang, Zhou, Ping, Zhou, Joan, Pitstick, Rose, Previti, Mary Lou, Younkin, Linda, Younkin, Steven G., Van Nostrand, William E., Cho, Sunghee, Anrather, Josef, Carlson, George A., Iadecola, Costantino
Cyhoeddwyd 2011

Persistent Amyloidosis following Suppression of Aβ Production in a Transgenic Model of Alzheimer Disease

gan Jankowsky, Joanna L, Slunt, Hilda H, Gonzales, Victoria, Savonenko, Alena V, Wen, Jason C, Jenkins, Nancy A, Copeland, Neal G, Younkin, Linda H, Lester, Henry A, Younkin, Steven G, Borchelt, David R
Cyhoeddwyd 2005

Involvement of β-site APP cleaving enzyme 1 (BACE1) in amyloid precursor protein-mediated enhancement of memory and activity-dependent synaptic plasticity

gan Ma, Huifang, Lesné, Sylvain, Kotilinek, Linda, Steidl-Nichols, Jill V., Sherman, Mathew, Younkin, Linda, Younkin, Steven, Forster, Colleen, Sergeant, Nicolas, Delacourte, André, Vassar, Robert, Citron, Martin, Kofuji, Paulo, Boland, Linda M., Ashe, Karen H.
Cyhoeddwyd 2007

Fine mapping of the α-T catenin gene to a quantitative trait locus on chromosome 10 in late-onset Alzheimer’s disease pedigrees

gan Ertekin-Taner, Nilüfer, Ronald, James, Asahara, Hideaki, Younkin, Linda, Hella, Maria, Jain, Shushant, Gnida, Eugene, Younkin, Samuel, Fadale, Daniel, Ohyagi, Yasumasa, Singleton, Adam, Scanlin, Leah, de Andrade, Mariza, Petersen, Ronald, Graff-Radford, Neill, Hutton, Michael, Younkin, Steven
Cyhoeddwyd 2003

Cyclooxygenase-2 inhibition improves amyloid-β-mediated suppression of memory and synaptic plasticity

gan Kotilinek, Linda A., Westerman, Marcus A., Wang, Qinwen, Panizzon, Kimberly, Lim, Giselle P., Simonyi, Agnes, Lesne, Sylvain, Falinska, Agnieszka, Younkin, Linda H., Younkin, Steven G., Rowan, Michael, Cleary, James, Wallis, Roi Ann, Sun, GraceY., Cole, Greg, Frautschy, Sally, Anwyl, Roger, Ashe, Karen H.
Cyhoeddwyd 2008

Genetically-controlled Vesicle-Associated Membrane Protein 1 expression may contribute to Alzheimer’s pathophysiology and susceptibility

gan Sevlever, Daniel, Zou, Fanggeng, Ma, Li, Carrasquillo, Sebastian, Crump, Michael G, Culley, Oliver J, Hunter, Talisha A, Bisceglio, Gina D, Younkin, Linda, Allen, Mariet, Carrasquillo, Minerva M, Sando, Sigrid B, Aasly, Jan O, Dickson, Dennis W, Graff-Radford, Neill R, Petersen, Ronald C, Belbin, Olivia
Cyhoeddwyd yn Mol Neurodegener (2015)