Critical threshold levels of DNA methyltransferase 1 are required to maintain DNA methylation across the genome in human cancer cells

Autor Cai, Yi, Tsai, Hsing-Chen, Yen, Ray-Whay Chiu, Zhang, Yang W., Kong, Xiangqian, Wang, Wei, Xia, Limin, Baylin, Stephen B.
Vydáno v Genome Res (2017)

A potential tumor suppressor role for Hic1 in breast cancer through transcriptional repression of ephrin-A1

Autor Zhang, Wei, Zeng, Xiaobei, Briggs, Kimberly J, Beaty, Robert, Simons, Brian, Yen, Ray-Whay Chiu, Tyler, Megan A, Tsai, Hsing-Chen, Ye, Ying, Gesell, Gregory S, Herman, James G, Baylin, Stephen B, Watkins, D Neil
Vydáno 2010

Pharmacologic induction of innate immune signaling directly drives homologous recombination deficiency

Autor McLaughlin, Lena J., Stojanovic, Lora, Kogan, Aksinija A., Rutherford, Julia L., Choi, Eun Yong, Yen, Ray-Whay Chiu, Xia, Limin, Zou, Ying, Lapidus, Rena G., Baylin, Stephen B., Topper, Michael J., Rassool, Feyruz V.
Vydáno v Proc Natl Acad Sci U S A (2020)

DNA methylation patterns separate senescence from transformation potential and indicate cancer risk

Autor Xie, Wenbing, Kagiampakis, Ioannis, Pan, Lixia, Zhang, Yang W., Murphy, Lauren, Tao, Yong, Kong, Xiangqian, Xia, Limin, Carvalho, Filipe LF, Sen, Subhojit, Yen, Ray-Whay Chiu, Zahnow, Cynthia A., Ahuja, Nita, Baylin, Stephen B., Easwaran, Hariharan
Vydáno v Cancer Cell (2018)

CHD4 Has Oncogenic Functions in Initiating and Maintaining Epigenetic Suppression of Multiple Tumor Suppressor Genes

Autor Xia, Limin, Huang, Wenjie, Bellani, Marina, Seidman, Michael M., Wu, Kaichun, Fan, Daiming, Nie, Yongzhan, Cai, Yi, Zhang, Yang W., Yu, Li-Rong, Li, Huili, Zahnow, Cynthia A., Xie, Wenbing, Yen, Ray-Whay Chiu, Rassool, Feyruz V., Baylin, Stephen B.
Vydáno v Cancer Cell (2017)

Defining UHRF1 Domains That Support Maintenance of Human Colon Cancer DNA Methylation and Oncogenic Properties

Autor Kong, Xiangqian, Chen, Jie, Xie, Wenbing, Brown, Stephen M., Cai, Yi, Wu, Kaichun, Fan, Daiming, Nie, Yongzhan, Yegnasubramanian, Srinivasan, Tiedemann, Rochelle L., Tao, Yong, Yen, Ray-Whay Chiu, Topper, Michael J., Zahnow, Cynthia A., Easwaran, Hariharan, Rothbart, Scott B., Xia, Limin, Baylin, Stephen B.
Vydáno v Cancer Cell (2019)

Immune regulation by low doses of the DNA methyltransferase inhibitor 5-azacitidine in common human epithelial cancers

Autor Li, Huili, Chiappinelli, Katherine B., Guzzetta, Angela A., Easwaran, Hariharan, Yen, Ray-Whay Chiu, Vatapalli, Rajita, Topper, Michael J., Luo, Jianjun, Connolly, Roisin M., Azad, Nilofer S., Stearns, Vered, Pardoll, Drew M., Davidson, Nancy, Jones, Peter A., Slamon, Dennis J., Baylin, Stephen B., Zahnow, Cynthia A., Ahuja, Nita
Vydáno 2014

Epigenetic Therapy Ties MYC Depletion to Reversing Immune Evasion and Treating Lung Cancer

Autor Topper, Michael J., Vaz, Michelle, Chiappinelli, Katherine B., DeStefano Shields, Christina E., Niknafs, Noushin, Yen, Ray-Whay Chiu, Wenzel, Alyssa, Hicks, Jessica, Ballew, Matthew, Stone, Meredith, Tran, Phuoc T., Zahnow, Cynthia A., Hellmann, Matthew D., Anagnostou, Valsamo, Strissel, Pamela L., Strick, Reiner, Velculescu, Victor E., Baylin, Stephen B.
Vydáno v Cell (2017)

Aging-like Spontaneous Epigenetic Silencing Facilitates Wnt Activation, Stemness, and Braf(V600E)-Induced Tumorigenesis

Autor Tao, Yong, Kang, Byunghak, Petkovich, Daniel A., Bhandari, Yuba R., In, Julie, Brien, Genevieve Stein-O’, Kong, Xiangqian, Xie, Wenbing, Zachos, Nicholas, Maegawa, Shinji, Vaidya, Himani, Brown, Stephen, Yen, Ray-Whay Chiu, Shao, Xiaojian, Thakor, Jai, Lu, Zhihao, Cai, Yi, Zhang, Yuezheng, Mallona, Izaskun, Peinado, Miguel Angel, Zahnow, Cynthia A., Ahuja, Nita, Fertig, Elana, Issa, Jean-Pierre, Baylin, Stephen B., Easwaran, Hariharan
Vydáno v Cancer Cell (2019)

Transient Low Doses of DNA Demethylating Agents Exert Durable Anti-tumor Effects on Hematological and Epithelial Tumor Cells

Autor Tsai, Hsing-Chen, Li, Huili, Van Neste, Leander, Cai, Yi, Robert, Carine, Rassool, Feyruz V., Shin, James J., Harbom, Kirsten M., Beaty, Robert, Pappou, Emmanouil, Harris, James, Yen, Ray-Whay Chiu, Ahuja, Nita, Brock, Malcolm V., Stearns, Vered, Feller-Kopman, David, Yarmus, Lonny B., Lin, Yi-Chun, Welm, Alana L., Issa, Jean-Pierre, Minn, Il, Matsui, William, Jang, Yoon-Young, Sharkis, Saul J., Baylin, Stephen B., Zahnow, Cynthia A.
Vydáno 2012