DNA methylation patterns separate senescence from transformation potential and indicate cancer risk

Overall shared DNA methylation patterns between senescence (Sen) and cancers have led to the model that tumor promoting epigenetic patterns arise through senescence. We show that transformation-associated methylation changes arise stochastically and independently of programmatic changes during senes...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cancer Cell
मुख्य लेखकों: Xie, Wenbing, Kagiampakis, Ioannis, Pan, Lixia, Zhang, Yang W., Murphy, Lauren, Tao, Yong, Kong, Xiangqian, Xia, Limin, Carvalho, Filipe LF, Sen, Subhojit, Yen, Ray-Whay Chiu, Zahnow, Cynthia A., Ahuja, Nita, Baylin, Stephen B., Easwaran, Hariharan
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2018
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5813821/
https://ncbi.nlm.nih.gov/pubmed/29438699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2018.01.008
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