Critical threshold levels of DNA methyltransferase 1 are required to maintain DNA methylation across the genome in human cancer cells

Reversing DNA methylation abnormalities and associated gene silencing, through inhibiting DNA methyltransferases (DNMTs) is an important potential cancer therapy paradigm. Maximizing this potential requires defining precisely how these enzymes maintain genome-wide, cancer-specific DNA methylation. T...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Cai, Yi, Tsai, Hsing-Chen, Yen, Ray-Whay Chiu, Zhang, Yang W., Kong, Xiangqian, Wang, Wei, Xia, Limin, Baylin, Stephen B.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5378172/
https://ncbi.nlm.nih.gov/pubmed/28232479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.208108.116
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados