Extracellular matrix composition determines the transcriptional response to epidermal growth factor receptor activation

Yazar: Yarwood, Stephen J., Woodgett, James R.
Baskı/Yayın Bilgisi 2001

The role of c-Jun in controlling the EPAC1-dependent induction of the SOCS3 gene in HUVECs

Yazar: Wiejak, Jolanta, Dunlop, Julia, Yarwood, Stephen J.
Baskı/Yayın Bilgisi 2014

EPAC proteins transduce diverse cellular actions of cAMP

Yazar: Borland, Gillian, Smith, Brian O, Yarwood, Stephen J
Baskı/Yayın Bilgisi 2009

Interaction with receptor for activated C-kinase 1 (RACK1) sensitizes the phosphodiesterase PDE4D5 towards hydrolysis of cAMP and activation by protein kinase C

Yazar: Bird, Rebecca J., Baillie, George S., Yarwood, Stephen J.
Baskı/Yayın Bilgisi 2010

The cAMP sensors, EPAC1 and EPAC2, display distinct subcellular distributions despite sharing a common nuclear pore localisation signal

Yazar: Parnell, Euan, Smith, Brian O., Yarwood, Stephen J.
Yayımlandı Cell Signal (2015)

The future of EPAC-targeted therapies: agonism versus antagonism

Yazar: Parnell, Euan, Palmer, Timothy M., Yarwood, Stephen J.
Yayımlandı Trends Pharmacol Sci (2015)

Flavanoids induce expression of the suppressor of cytokine signalling 3 (SOCS3) gene and suppress IL-6-activated signal transducer and activator of transcription 3 (STAT3) activati...

Yazar: Wiejak, Jolanta, Dunlop, Julia, Mackay, Simon P., Yarwood, Stephen J.
Baskı/Yayın Bilgisi 2013

Selective small-molecule EPAC activators

Yazar: Luchowska-Stańska, Urszula, Morgan, David, Yarwood, Stephen J., Barker, Graeme
Yayımlandı Biochem Soc Trans (2019)

Genome-Wide Mapping Defines a Role for C/EBPβ and c-Jun in Non-Canonical Cyclic AMP Signalling

Yazar: Wiejak, Jolanta, van Basten, Boy, Hamilton, Graham, Yarwood, Stephen J.
Yayımlandı Cells (2019)

Activation of Protein Kinase Cα by EPAC1 Is Required for the ERK- and CCAAT/Enhancer-binding Protein β-dependent Induction of the SOCS-3 Gene by Cyclic AMP in COS1 Cells

Yazar: Borland, Gillian, Bird, Rebecca J., Palmer, Timothy M., Yarwood, Stephen J.
Baskı/Yayın Bilgisi 2009

The novel exchange protein activated by cyclic AMP 1 (EPAC1) agonist, I942, regulates inflammatory gene expression in human umbilical vascular endothelial cells (HUVECs)

Yazar: Wiejak, Jolanta, van Basten, Boy, Luchowska-Stańska, Urszula, Hamilton, Graham, Yarwood, Stephen J.
Yayımlandı Biochim Biophys Acta Mol Cell Res (2019)

Exchange protein directly activated by cAMP (EPAC) interacts with the light chain (LC) 2 of MAP1A

Yazar: Magiera, Maria M., Gupta, Mona, Rundell, Catherine J., Satish, Nilima, Ernens, Isabelle, Yarwood, Stephen J.
Baskı/Yayın Bilgisi 2004

Regulation of the inflammatory response of vascular endothelial cells by EPAC1

Yazar: Parnell, Euan, Smith, Brian O, Palmer, Timothy M, Terrin, Anna, Zaccolo, Manuela, Yarwood, Stephen J
Baskı/Yayın Bilgisi 2012

Genomic analysis of the role of transcription factor C/EBPδ in the regulation of cell behaviour on nanometric grooves

Yazar: Wiejak, Jolanta, Tsimbouri, Penelope M., Herzyk, Pawel, Dalby, Matthew J., Hamilton, Graham, Yarwood, Stephen J.
Baskı/Yayın Bilgisi 2013

The Potential of a Novel Class of EPAC-Selective Agonists to Combat Cardiovascular Inflammation

Yazar: Barker, Graeme, Parnell, Euan, van Basten, Boy, Buist, Hanna, Adams, David R., Yarwood, Stephen J.
Yayımlandı J Cardiovasc Dev Dis (2017)

Serine-727 Phosphorylation Activates Hypothalamic STAT-3 Independently From Tyrosine-705 Phosphorylation

Yazar: Breit, Andreas, Besik, Valeria, Solinski, Hans Jürgen, Muehlich, Susanne, Glas, Evi, Yarwood, Stephen J., Gudermann, Thomas
Yayımlandı Mol Endocrinol (2015)

Delineation of RAID1, the RACK1 interaction domain located within the unique N-terminal region of the cAMP-specific phosphodiesterase, PDE4D5

Yazar: Bolger, Graeme B, McCahill, Angela, Yarwood, Stephen J, Steele, Michael R, Warwicker, Jim, Houslay, Miles D
Baskı/Yayın Bilgisi 2002

Stimulation of p70S6 kinase via a growth hormone-controlled phosphatidylinositol 3-kinase pathway leads to the activation of a PDE4A cyclic AMP-specific phosphodiesterase in 3T3-F4...

Yazar: MacKenzie, Simon J., Yarwood, Stephen J., Peden, Alexander H., Bolger, Graeme B., Vernon, Richard G., Houslay, Miles D.
Baskı/Yayın Bilgisi 1998

The protein kinase C inhibitor, Ro-31-7459, is a potent activator of ERK and JNK MAP kinases in HUVECs and yet inhibits cyclic AMP-stimulated SOCS-3 gene induction through inactiva...

Yazar: Wiejak, Jolanta, Dunlop, Julia, Stoyle, Chloe, Lappin, Gillian, McIlroy, Anna, Pediani, John D., Gao, Shan, Yarwood, Stephen J.
Baskı/Yayın Bilgisi 2012

Phosphorylation of ezrin on Thr567 is required for the synergistic activation of cell spreading by EPAC1 and protein kinase A in HEK293T cells

Yazar: Parnell, Euan, Koschinski, Andreas, Zaccolo, Manuela, Cameron, Ryan T., Baillie, George S., Baillie, Gemma L., Porter, Alison, McElroy, Stuart P., Yarwood, Stephen J.
Yayımlandı Biochim Biophys Acta (2015)