Llwytho...
Flavanoids induce expression of the suppressor of cytokine signalling 3 (SOCS3) gene and suppress IL-6-activated signal transducer and activator of transcription 3 (STAT3) activation in vascular endothelial cells
The atherogenic cytokine IL-6 (interleukin-6) induces pro-inflammatory gene expression in VECs (vascular endothelial cells) by activating the JAK (Janus kinase)/STAT3 (signal transducer and activator of transcription 3) signalling pathway, which is normally down-regulated by the STAT3-dependent indu...
Wedi'i Gadw mewn:
Prif Awduron: | , , , |
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Fformat: | Artigo |
Iaith: | Inglês |
Cyhoeddwyd: |
Portland Press Ltd.
2013
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3749869/ https://ncbi.nlm.nih.gov/pubmed/23782265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20130481 |
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