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The role of c-Jun in controlling the EPAC1-dependent induction of the SOCS3 gene in HUVECs
The cyclic AMP sensor, EPAC1, activates AP1-mediated transcription in HUVECs. Correspondingly, induction of the SOCS3 minimal promoter by EPAC1 requires a single AP1 site that constitutively binds phosphorylated (Ser63) c-Jun in DNA-pull-down assays. c-Jun (Ser63) becomes further phosphorylated foll...
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| Main Authors: | , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Elsevier Science B.V
2014
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4005914/ https://ncbi.nlm.nih.gov/pubmed/24631457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2014.02.038 |
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