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The biology and mechanism of action of Suppressor of Cytokine Signaling 3 (SOCS3)
SOCS3 has been shown to be an important and non-redundant feedback inhibitor of several cytokines including LIF, IL-6, IL-11, CNTF, leptin and G-CSF. Loss of SOCS3 in vivo has profound effects on placental development, inflammation, fat-induced weight gain and insulin sensitivity. SOCS3 expression i...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3757090/ https://ncbi.nlm.nih.gov/pubmed/22574771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08977194.2012.687375 |
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