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Inhibition of IL-6 family cytokines by SOCS3
IL-6 a multi-functional cytokine with important effects in both inflammation and haematopoiesis. SOCS3 is the primary inhibitor of IL-6 signalling, interacting with gp130, the common shared chain of the IL-6 family of cytokines, and JAK1, JAK2 and TYK2 to control both the duration of signalling and...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3970923/ https://ncbi.nlm.nih.gov/pubmed/24418198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2013.12.004 |
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