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The future of EPAC-targeted therapies: agonism versus antagonism
Pharmaceutical manipulation of cAMP levels exerts beneficial effects through the regulation of the exchange protein activated by cAMP (EPAC) and protein kinase A (PKA) signalling routes. Recent attention has turned to the specific regulation of EPAC isoforms (EPAC1 and EPAC2) as a more targeted appr...
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| Vydáno v: | Trends Pharmacol Sci |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Published By Elsevier In Association With The International Union Of Pharmacology
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4392396/ https://ncbi.nlm.nih.gov/pubmed/25744542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2015.02.003 |
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