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Recent Advances in EPAC-Targeted Therapies: A Biophysical Perspective

The universal second messenger cAMP regulates diverse intracellular processes by interacting with ubiquitously expressed proteins, such as Protein Kinase A (PKA) and the Exchange Protein directly Activated by cAMP (EPAC). EPAC is implicated in multiple pathologies, thus several EPAC-specific inhibit...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Ahmed, Alveena, Boulton, Stephen, Shao, Hongzhao, Akimoto, Madoka, Natarajan, Amarnath, Cheng, Xiaodong, Melacini, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912387/
https://ncbi.nlm.nih.gov/pubmed/31752286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8111462
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