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Recent Advances in the Discovery of Small Molecules Targeting Exchange Proteins Directly Activated by cAMP (EPAC)

cAMP is a pivotal second messenger that regulates numerous biological processes under physiological and pathological conditions, including cancer, diabetes, heart failure, inflammation and neurological disorders. In the past, all effects of cAMP were initially believed to be mediated by PKA and cycl...

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Detalles Bibliográficos
Main Authors: Chen, Haijun, Wild, Christopher, Zhou, Xiaobin, Ye, Na, Cheng, Xiaodong, Zhou, Jia
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016168/
https://ncbi.nlm.nih.gov/pubmed/24256330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm401425e
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