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The pleiotropic role of exchange protein directly activated by cAMP 1 (EPAC1) in cancer: implications for therapeutic intervention

The pleiotropic second messenger adenosine 3′,5′-cyclic monophosphate (cAMP) regulates a myriad of biological processes under both physiological and pathophysiological conditions. Exchange protein directly activated by cAMP 1 (EPAC1) mediates the intracellular functions of cAMP by acting as a guanin...

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Detalhes bibliográficos
Publicado no:Acta Biochim Biophys Sin (Shanghai)
Main Authors: Almahariq, Muayad, Mei, Fang C., Cheng, Xiaodong
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4689159/
https://ncbi.nlm.nih.gov/pubmed/26525949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/abbs/gmv115
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