Inhibition of Non-ATG Translational Events in Cells via Covalent Small Molecules Targeting RNA

Autor Yang, Wang-Yong, Wilson, Henry D., Velagapudi, Sai Pradeep, Disney, Matthew D.
Vydáno v J Am Chem Soc (2015)

Design of a bioactive small molecule that targets r(AUUCU) repeats in spinocerebellar ataxia 10

Autor Yang, Wang-Yong, Gao, Rui, Southern, Mark, Sarkar, Partha S., Disney, Matthew D.
Vydáno v Nat Commun (2016)

Intracellular DNA Damage by Lysine-Acetylene Conjugates

Autor Yang, Wang-Yong, Cao, Qiang, Callahan, Catherine, Galvis, Catalina, Sang, Qing-Xiang, Alabugin, Igor V.
Vydáno 2010

Fine-tuning alkyne cycloadditions: Insights into photochemistry responsible for the double-strand DNA cleavage via structural perturbations in diaryl alkyne conjugates

Autor Yang, Wang-Yong, Marrone, Samantha A, Minors, Nalisha, Zorio, Diego A R, Alabugin, Igor V
Vydáno 2011

Small Molecule Inhibition of miR-544 Biogenesis Disrupts Adaptive Responses to Hypoxia by Modulating ATM-mTOR Signaling

Autor Haga, Christopher L., Velagapudi, Sai Pradeep, Strivelli, Jacqueline R., Yang, Wang-Yong, Disney, Matthew D., Phinney, Donald G.
Vydáno v ACS Chem Biol (2015)

A Small Molecule that Targets r(CGG)(exp) and Improves Defects in Fragile X-Associated Tremor Ataxia Syndrome

Autor Disney, Matthew D., Liu, Biao, Yang, Wang-Yong, Sellier, Chantal, Tran, Tuan, Charlet-Berguerand, Nicolas, Childs-Disney, Jessica L.
Vydáno 2012

Promoter-Bound Trinucleotide Repeat mRNA Drives Epigenetic Silencing in Fragile X Syndrome

Autor Colak, Dilek, Zaninovic, Nikica, Cohen, Michael S., Rosenwaks, Zev, Yang, Wang-Yong, Gerhardt, Jeannine, Disney, Matthew D., Jaffrey, Samie R.
Vydáno v Science (2014)

Small Molecule Recognition and Tools to Study Modulation of r(CGG)(exp) in Fragile X-Associated Tremor Ataxia Syndrome

Autor Yang, Wang-Yong, He, Fang, Strack, Rita L., Oh, Seok Yoon, Frazer, Michelle, Jaffrey, Samie R., Todd, Peter K., Disney, Matthew D.
Vydáno v ACS Chem Biol (2016)

C-Lysine Conjugates: pH-Controlled Light-Activated Reagents for Efficient Double Stranded DNA Cleavage with Implications for Cancer Therapy

Autor Yang, Wang-Yong, Breiner, Boris, Kovalenko, Serguei V., Ben, Chi, Singh, Mani, LeGrand, Shauna N., Sang, Qing-Xiang Amy, Strouse, Geoffrey F., Copland, John A., Alabugin, Igor V.
Vydáno 2009

The Hairpin Form of r(G(4)C(2))(exp) in c9ALS/FTD is Repeat-associated non-ATG Translated and a Target for Bioactive Small Molecules

Autor Wang, Zi-Fu, Ursu, Andrei, Childs-Disney, Jessica L., Guertler, Rea, Yang, Wang-Yong, Bernat, Viachaslau, Rzuczek, Suzanne G., Fuerst, Rita, Zhang, Yong-Jie, Gendron, Tania F., Yildirim, Ilyas, Dwyer, Brendan G., Rice, Joseph E., Petrucelli, Leonard, Disney, Matthew D.
Vydáno v Cell Chem Biol (2018)

Discovery of a Biomarker and Lead Small Molecules to Target r(GGGGCC)-Associated Defects in c9FTD/ALS

Autor Su, Zhaoming, Zhang, Yongjie, Gendron, Tania F., Bauer, Peter O., Chew, Jeannie, Yang, Wang-Yong, Fostvedt, Erik, Jansen-West, Karen, Belzil, Veronique V., Desaro, Pamela, Johnston, Amelia, Overstreet, Karen, Oh, Seok-Yoon, Todd, Peter K., Berry, James D., Cudkowicz, Merit E., Boeve, Bradley F., Dickson, Dennis, Floeter, Mary Kay, Traynor, Bryan J., Morelli, Claudia, Ratti, Antonia, Silani, Vincenzo, Rademakers, Rosa, Brown, Robert H., Rothstein, Jeffrey D., Boylan, Kevin B., Petrucelli, Leonard, Disney, Matthew D.
Vydáno v Neuron (2014)