Intracellular DNA Damage by Lysine-Acetylene Conjugates

Previously, we reported the design and properties of alkyne C-lysine conjugates, a powerful and tunable family of DNA cleaving reagents. We also reported that, upon photoactivation, these molecules are capable of inducing cancer cells death. To prove that the cell death stems from DNA cleavage by th...

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Detalles Bibliográficos
Main Authors: Yang, Wang-Yong, Cao, Qiang, Callahan, Catherine, Galvis, Catalina, Sang, Qing-Xiang, Alabugin, Igor V.
Formato: Artigo
Idioma:Inglês
Publicado: SAGE-Hindawi Access to Research 2010
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930354/
https://ncbi.nlm.nih.gov/pubmed/20814583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/931394
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