Intracellular DNA Damage by Lysine-Acetylene Conjugates

Previously, we reported the design and properties of alkyne C-lysine conjugates, a powerful and tunable family of DNA cleaving reagents. We also reported that, upon photoactivation, these molecules are capable of inducing cancer cells death. To prove that the cell death stems from DNA cleavage by th...

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מידע ביבליוגרפי
Main Authors: Yang, Wang-Yong, Cao, Qiang, Callahan, Catherine, Galvis, Catalina, Sang, Qing-Xiang, Alabugin, Igor V.
פורמט: Artigo
שפה:Inglês
יצא לאור: SAGE-Hindawi Access to Research 2010
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930354/
https://ncbi.nlm.nih.gov/pubmed/20814583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/931394
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