RNA structures as mediators of neurological diseases and as drug targets

Por Bernat, Viachaslau, Disney, Matthew D.
Publicado no Neuron (2015)

The Hairpin Form of r(G(4)C(2))(exp) in c9ALS/FTD is Repeat-associated non-ATG Translated and a Target for Bioactive Small Molecules

Por Wang, Zi-Fu, Ursu, Andrei, Childs-Disney, Jessica L., Guertler, Rea, Yang, Wang-Yong, Bernat, Viachaslau, Rzuczek, Suzanne G., Fuerst, Rita, Zhang, Yong-Jie, Gendron, Tania F., Yildirim, Ilyas, Dwyer, Brendan G., Rice, Joseph E., Petrucelli, Leonard, Disney, Matthew D.
Publicado no Cell Chem Biol (2018)

Structure–based discovery of opioid analgesics with reduced side effects

Por Manglik, Aashish, Lin, Henry, Aryal, Dipendra K., McCorvy, John D., Dengler, Daniela, Corder, Gregory, Levit, Anat, Kling, Ralf C., Bernat, Viachaslau, Hübner, Harald, Huang, Xi-Ping, Sassano, Maria F., Giguère, Patrick M., Löber, Stefan, Duan, Da, Scherrer, Grégory, Kobilka, Brian K., Gmeiner, Peter, Roth, Bryan L., Shoichet, Brian K.
Publicado no Nature (2016)