Important miRs of Pathways in Different Tumor Types

Por Wuchty, Stefan, Arjona, Dolores, Bauer, Peter O.
Publicado em 2013

Involvement of microRNA families in cancer

Por Wuchty, Stefan, Arjona, Dolores, Bozdag, Serdar, Bauer, Peter O.
Publicado em 2012

Quantitative Real-Time PCR Analysis of YKL-40 and Its Comparison with Mammalian Chitinase mRNAs in Normal Human Tissues Using a Single Standard DNA

Por Ohno, Misa, Bauer, Peter O., Kida, Yuta, Sakaguchi, Masayoshi, Sugahara, Yasusato, Oyama, Fumitaka
Publicado no Int J Mol Sci (2015)

ROCK-phosphorylated vimentin modifies mutant huntingtin aggregation via sequestration of IRBIT

Por Bauer, Peter O, Hudec, Roman, Goswami, Anand, Kurosawa, Masaru, Matsumoto, Gen, Mikoshiba, Katsuhiko, Nukina, Nobuyuki
Publicado em 2012

A novel form of ciliopathy underlies hyperphagia and obesity in Ankrd26 knockout mice

Por Acs, Peter, Bauer, Peter O., Mayer, Balazs, Bera, Tapan, Macallister, Rhonda, Mezey, Eva, Pastan, Ira
Publicado no Brain Struct Funct (2014)

Characterization of DNA hypermethylation in the cerebellum of c9FTD/ALS patients

Por Belzil, Veronique V., Bauer, Peter O., Gendron, Tania F., Murray, Melissa E., Dickson, Dennis, Petrucelli, Leonard
Publicado em 2014

Inhibition of Rho Kinases Enhances the Degradation of Mutant Huntingtin

Por Bauer, Peter O., Wong, Hon Kit, Oyama, Fumitaka, Goswami, Anand, Okuno, Misako, Kino, Yoshihiro, Miyazaki, Haruko, Nukina, Nobuyuki
Publicado em 2009

Large-Scale RNA Interference Screening in Mammalian Cells Identifies Novel Regulators of Mutant Huntingtin Aggregation

Por Yamanaka, Tomoyuki, Wong, Hon Kit, Tosaki, Asako, Bauer, Peter O., Wada, Koji, Kurosawa, Masaru, Shimogori, Tomomi, Hattori, Nobutaka, Nukina, Nobuyuki
Publicado em 2014

Loss and Gain of Human Acidic Mammalian Chitinase Activity by Nonsynonymous SNPs

Por Okawa, Kazuaki, Ohno, Misa, Kashimura, Akinori, Kimura, Masahiro, Kobayashi, Yuki, Sakaguchi, Masayoshi, Sugahara, Yasusato, Kamaya, Minori, Kino, Yoshihiro, Bauer, Peter O., Oyama, Fumitaka
Publicado no Mol Biol Evol (2016)

Functional Properties of the Catalytic Domain of Mouse Acidic Mammalian Chitinase Expressed in Escherichia coli

Por Kashimura, Akinori, Kimura, Masahiro, Okawa, Kazuaki, Suzuki, Hirotaka, Ukita, Atsushi, Wakita, Satoshi, Okazaki, Kana, Ohno, Misa, Bauer, Peter O., Sakaguchi, Masayoshi, Sugahara, Yasusato, Oyama, Fumitaka
Publicado no Int J Mol Sci (2015)

Functional Properties of Mouse Chitotriosidase Expressed in the Periplasmic Space of Escherichia coli

Por Kimura, Masahiro, Wakita, Satoshi, Ishikawa, Kotarou, Sekine, Kazutaka, Yoshikawa, Satoshi, Sato, Akira, Okawa, Kazuaki, Kashimura, Akinori, Sakaguchi, Masayoshi, Sugahara, Yasusato, Yamanaka, Daisuke, Ohno, Naohito, Bauer, Peter O, Oyama, Fumitaka
Publicado no PLoS One (2016)

Acidic mammalian chitinase is a proteases-resistant glycosidase in mouse digestive system

Por Ohno, Misa, Kimura, Masahiro, Miyazaki, Haruko, Okawa, Kazuaki, Onuki, Riho, Nemoto, Chiyuki, Tabata, Eri, Wakita, Satoshi, Kashimura, Akinori, Sakaguchi, Masayoshi, Sugahara, Yasusato, Nukina, Nobuyuki, Bauer, Peter O., Oyama, Fumitaka
Publicado no Sci Rep (2016)

The extreme N-terminus of TDP-43 mediates the cytoplasmic aggregation of TDP-43 and associated toxicity in vivo

Por Sasaguri, Hiroki, Chew, Jeannie, Xu, Ya-Fei, Gendron, Tania F., Garrett, Aliesha, Lee, Chris W., Jansen-West, Karen, Bauer, Peter O., Perkerson, Emilie A., Tong, Jimei, Stetler, Caroline, Zhang, Yong-Jie
Publicado no Brain Res (2016)

Reduced C9orf72 gene expression in c9FTD/ALS is caused by histone trimethylation, an epigenetic event detectable in blood

Por Belzil, Veronique V., Bauer, Peter O., Prudencio, Mercedes, Gendron, Tania F., Stetler, Caroline T., Yan, Irene K., Pregent, Luc, Daughrity, Lillian, Baker, Matthew C., Rademakers, Rosa, Boylan, Kevin, Patel, Tushar C., Dickson, Dennis W., Petrucelli, Leonard
Publicado em 2013

De Novo Mutations in Ataxin-2 Gene and ALS Risk

Por Laffita-Mesa, José Miguel, Rodríguez Pupo, Jorge Michel, Moreno Sera, Raciel, Vázquez Mojena, Yaimee, Kourí, Vivian, Laguna-Salvia, Leonides, Martínez-Godales, Michael, Valdevila Figueira, José A., Bauer, Peter O., Rodríguez-Labrada, Roberto, Zaldívar, Yanetza González, Paucar, Martin, Svenningsson, Per, Pérez, Luís Velázquez
Publicado em 2013

Targeted manipulation of the sortilin–progranulin axis rescues progranulin haploinsufficiency

Por Lee, Wing C., Almeida, Sandra, Prudencio, Mercedes, Caulfield, Thomas R., Zhang, Yong-Jie, Tay, William M., Bauer, Peter O., Chew, Jeannie, Sasaguri, Hiroki, Jansen-West, Karen R., Gendron, Tania F., Stetler, Caroline T., Finch, NiCole, Mackenzie, Ian R., Rademakers, Rosa, Gao, Fen-Biao, Petrucelli, Leonard
Publicado em 2014

(Patho-)physiological relevance of PINK1-dependent ubiquitin phosphorylation

Por Fiesel, Fabienne C, Ando, Maya, Hudec, Roman, Hill, Anneliese R, Castanedes-Casey, Monica, Caulfield, Thomas R, Moussaud-Lamodière, Elisabeth L, Stankowski, Jeannette N, Bauer, Peter O, Lorenzo-Betancor, Oswaldo, Ferrer, Isidre, Arbelo, José M, Siuda, Joanna, Chen, Li, Dawson, Valina L, Dawson, Ted M, Wszolek, Zbigniew K, Ross, Owen A, Dickson, Dennis W, Springer, Wolfdieter
Publicado no EMBO Rep (2015)

Associations of repeat sizes with clinical and pathological characteristics in C9ORF72 expansion carriers (Xpansize-72): a cross-sectional cohort study

Por van Blitterswijk, Marka, DeJesus-Hernandez, Mariely, Niemantsverdriet, Ellis, Murray, Melissa E, Heckman, Michael G, Diehl, Nancy N, Brown, Patricia H, Baker, Matthew C, Finch, NiCole A, Bauer, Peter O, Serrano, Geidy, Beach, Thomas G, Josephs, Keith A, Knopman, David S, Petersen, Ronald C, Boeve, Bradley F, Graff-Radford, Neill R, Boylan, Kevin B, Petrucelli, Leonard, Dickson, Dennis W, Rademakers, Rosa
Publicado em 2013

C9ORF72 repeat expansions in mice cause TDP-43 pathology, neuronal loss, and behavioral deficits

Por Chew, Jeannie, Gendron, Tania F., Prudencio, Mercedes, Sasaguri, Hiroki, Zhang, Yong-Jie, Castanedes-Casey, Monica, Lee, Chris W., Jansen-West, Karen, Kurti, Aishe, Murray, Melissa E., Bieniek, Kevin F., Bauer, Peter O., Whitelaw, Ena C., Rousseau, Linda, Stankowski, Jeannette N., Stetler, Caroline, Daughrity, Lillian M., Perkerson, Emilie A., Desaro, Pamela, Johnston, Amelia, Overstreet, Karen, Edbauer, Dieter, Rademakers, Rosa, Boylan, Kevin B., Dickson, Dennis W., Fryer, John D., Petrucelli, Leonard
Publicado no Science (2015)

Discovery of a Biomarker and Lead Small Molecules to Target r(GGGGCC)-Associated Defects in c9FTD/ALS

Por Su, Zhaoming, Zhang, Yongjie, Gendron, Tania F., Bauer, Peter O., Chew, Jeannie, Yang, Wang-Yong, Fostvedt, Erik, Jansen-West, Karen, Belzil, Veronique V., Desaro, Pamela, Johnston, Amelia, Overstreet, Karen, Oh, Seok-Yoon, Todd, Peter K., Berry, James D., Cudkowicz, Merit E., Boeve, Bradley F., Dickson, Dennis, Floeter, Mary Kay, Traynor, Bryan J., Morelli, Claudia, Ratti, Antonia, Silani, Vincenzo, Rademakers, Rosa, Brown, Robert H., Rothstein, Jeffrey D., Boylan, Kevin B., Petrucelli, Leonard, Disney, Matthew D.
Publicado no Neuron (2014)