RAN translation at CGG repeats induces ubiquitin proteasome system impairment in models of fragile X-associated tremor ataxia syndrome

Por Oh, Seok Yoon, He, Fang, Krans, Amy, Frazer, Michelle, Taylor, J. Paul, Paulson, Henry L., Todd, Peter K.
Publicado no Hum Mol Genet (2015)

The carboxyl termini of RAN translated GGGGCC nucleotide repeat expansions modulate toxicity in models of ALS/FTD

Por He, Fang, Flores, Brittany N., Krans, Amy, Frazer, Michelle, Natla, Sam, Niraula, Sarjina, Adefioye, Olamide, Barmada, Sami J., Todd, Peter K.
Publicado no Acta Neuropathol Commun (2020)

Small Molecule Recognition and Tools to Study Modulation of r(CGG)(exp) in Fragile X-Associated Tremor Ataxia Syndrome

Por Yang, Wang-Yong, He, Fang, Strack, Rita L., Oh, Seok Yoon, Frazer, Michelle, Jaffrey, Samie R., Todd, Peter K., Disney, Matthew D.
Publicado no ACS Chem Biol (2016)

Abnormal locus coeruleus activity during sleep alters sleep signatures of memory consolidation and impairs place cell stability and spatial memory

Por Swift, Kevin M., Gross, Brooks A., Frazer, Michelle, Bauer, David S., Clark, Kyle, Vazey, Elena, Aston-Jones, Gary, Li, Yong, Pickering, Anthony E., Sara, Susan, Poe, Gina R.
Publicado no Curr Biol (2018)

CGG Repeat Associated Translation Mediates Neurodegeneration in Fragile X Tremor Ataxia Syndrome

Por Todd, Peter K., Oh, Seok Yoon, Krans, Amy, He, Fang, Sellier, Chantal, Frazer, Michelle, Renoux, Abigail J., Chen, Kai-chun, Scaglione, K. Matthew, Basrur, Venkatesha, Elenitoba-Johnson, Kojo, Vonsattel, Jean P., Louis, Elan D., Sutton, Michael A., Taylor, J. Paul, Mills, Ryan E., Charlet-Berguerand, Nicholas, Paulson, Henry L.
Publicado em 2013