How regulatory T cells work

Por Vignali, Dario A. A., Collison, Lauren W., Workman, Creg J.
Publicado em 2008

Remodulation of the tumor microenvironment by regulatory T cells

Por Liu, Chang, Chikina, Maria, Workman, Creg J, Vignali, Dario AA
Publicado no J Immunother Cancer (2015)

CUTTING EDGE: REGULATORY T CELLS DO NOT REQUIRE STIMULATION THROUGH THEIR T CELL RECEPTOR TO SUPPRESS

Por Szymczak-Workman, Andrea L., Workman, Creg J., Vignali, Dario A. A.
Publicado em 2009

The extent of metalloproteinase-mediated LAG3 cleavage limits the efficacy of PD1 blockade

Por Andrews, Lawrence P, Szymczak-Workman, Andrea L, Workman, Creg J, Vignali, Dario AA
Publicado no J Immunother Cancer (2015)

Human Regulatory T Cells Require Interleukin-35 to Mediate Suppression and Infectious Tolerance

Por Chaturvedi, Vandana, Collison, Lauren W., Guy, Clifford S., Workman, Creg J., Vignali, Dario A. A.
Publicado em 2011

Retraction: Human Regulatory T Cells Require IL-35 To Mediate Suppression and Infectious Tolerance

Por Chaturvedi, Vandana, Collison, Lauren W., Guy, Clifford S., Workman, Creg J., Vignali, Dario A. A.
Publicado no J Immunol (2013)

The Development and Function of Regulatory T Cells

Por Workman, Creg J., Szymczak-Workman, Andrea L., Collison, Lauren W., Pillai, Meenu R., Vignali, Dario A.A.
Publicado em 2009

CNS Destruction Mediated by GAD-Specific CD4(+) T Cells

Por Burton, Amanda R., Baquet, Zachary, Eisenbarth, George S., Tisch, Roland, Smeyne, Richard, Workman, Creg J., Vignali, Dario A.A.
Publicado em 2010

In Vivo Treg Suppression Assays

Por Workman, Creg J., Collison, Lauren W., Bettini, Maria, Pillai, Meenu R., Rehg, Jerold E., Vignali, Dario A.A.
Publicado em 2011

LAG-3, TGF-β, and cell-intrinsic PD-1 inhibitory pathways contribute to CD8 but not CD4 T-cell tolerance induced by allogeneic BMT with anti-CD40L

Por Lucas, Carrie L., Workman, Creg J., Beyaz, Semir, LoCascio, Samuel, Zhao, Guiling, Vignali, Dario A. A., Sykes, Megan
Publicado em 2011

Modulation of Redox Balance Leaves Murine Diabetogenic TH1 T Cells “LAG-3-ing” Behind

Por Delmastro, Meghan M., Styche, Alexis J., Trucco, Massimo M., Workman, Creg J., Vignali, Dario A.A., Piganelli, Jon D.
Publicado em 2012

Lymphocyte Activation Gene-3 (LAG-3) Negatively Regulates Environmentally-Induced Autoimmunity

Por Jha, Vibha, Workman, Creg J., McGaha, Tracy L., Li, Liping, Vas, Jaya, Vignali, Dario A. A., Monestier, Marc
Publicado em 2014

Differential subcellular localization of the regulatory T-cell protein LAG-3 and the coreceptor CD4

Por Woo, Seng-Ryong, Li, Nianyu, Bruno, Tullia C., Forbes, Karen, Brown, Scott, Workman, Creg, Drake, Charles G., Vignali, Dario A. A.
Publicado em 2010

LAG-3 Regulates Plasmacytoid Dendritic Cell Homeostasis

Por Workman, Creg J., Wang, Yao, El Kasmi, Karim C., Pardoll, Drew M., Murray, Peter J., Drake, Charles G., Vignali, Dario A.A.
Publicado em 2009

Kinetics of Alloantigen-Specific Regulatory CD4 T Cell Development and Tissue Distribution After Donor-Specific Transfusion and Costimulatory Blockade

Por Tomita, Yusuke, Satomi, Miwa, Baran, William Bracamonte, Jankowska Gan, Ewa, Workman, Andrea Szymczak, Workman, Creg J., Vignali, Dario Angelo Alberto, Burlingham, William J.
Publicado no Transplant Direct (2016)

Coregulation of CD8(+) T cell exhaustion during chronic viral infection by multiple inhibitory receptors

Por Blackburn, Shawn D., Shin, Haina, Haining, W. Nicholas, Zou, Tao, Workman, Creg J., Polley, Antonio, Betts, Michael R., Freeman, Gordon J., Vignali, Dario A. A., Wherry, E. John
Publicado em 2008

Identification of the Docking Site for CD3 on the T Cell Receptor β Chain by Solution NMR

Por He, Yanan, Rangarajan, Sneha, Kerzic, Melissa, Luo, Ming, Chen, Yihong, Wang, Qian, Yin, Yiyuan, Workman, Creg J., Vignali, Kate M., Vignali, Dario A. A., Mariuzza, Roy A., Orban, John
Publicado no J Biol Chem (2015)

TIM-1 signaling is required for Maintenance and Induction of regulatory B cells

Por Yeung, Melissa Y., Ding, Qing, Brooks, Craig R., Xiao, Sheng, Workman, Creg J., Vignali, Dario A.A., Ueno, Takuya, Padera, Robert F., Kuchroo, Vijay K., Najafian, Nader, Rothstein, David M.
Publicado no Am J Transplant (2015)

Interleukin-35 limits anti-tumor immunity

Por Turnis, Meghan E., Sawant, Deepali V., Szymczak-Workman, Andrea L., Andrews, Lawrence P., Delgoffe, Greg M., Yano, Hiroshi, Beres, Amy J., Vogel, Peter, Workman, Creg J., Vignali, Dario A. A.
Publicado no Immunity (2016)

Regulatory T cell stability is maintained by a neuropilin-1:semaphorin-4a axis

Por Delgoffe, Greg M., Woo, Seng-Ryong, Turnis, Meghan E., Gravano, David M., Guy, Cliff, Overacre, Abigail E., Bettini, Matthew L., Vogel, Peter, Finkelstein, David, Bonnevier, Jody, Workman, Creg J., Vignali, Dario A.A.
Publicado em 2013