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Human Regulatory T Cells Require Interleukin-35 to Mediate Suppression and Infectious Tolerance

Human regulatory T cells (T(regs)) are essential for the maintenance of immune tolerance. However, the mechanisms they use to mediate suppression remain controversial. Although IL-35 has been shown to play an important role in T(reg)-mediated suppression in mice, recent studies have questioned its r...

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Main Authors: Chaturvedi, Vandana, Collison, Lauren W., Guy, Clifford S., Workman, Creg J., Vignali, Dario A. A.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110563/
https://ncbi.nlm.nih.gov/pubmed/21576509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100315
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