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CUTTING EDGE: REGULATORY T CELLS DO NOT REQUIRE STIMULATION THROUGH THEIR T CELL RECEPTOR TO SUPPRESS

The mechanism and stimulatory requirements of regulatory T cell (Treg)-mediated suppression are still unclear. To assess the requirement for Treg stimulation by cognate peptide:MHC, we used T cells from OTII and AND TCR transgenic mice that are specific for and restricted by distinct, non-crossreact...

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Hlavní autoři: Szymczak-Workman, Andrea L., Workman, Creg J., Vignali, Dario A. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745156/
https://ncbi.nlm.nih.gov/pubmed/19380762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803123
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