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The Development and Function of Regulatory T Cells

Regulatory T cells [Tregs] are a critical subset of T cells that mediate peripheral tolerance. There are two types of Tregs: natural Tregs, which develop in the thymus, and induced Tregs, which are derived from naïve CD4(+) T cells in the periphery. Tregs utilize a variety of mechanisms to suppress...

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Bibliografiske detaljer
Main Authors: Workman, Creg J., Szymczak-Workman, Andrea L., Collison, Lauren W., Pillai, Meenu R., Vignali, Dario A.A.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715449/
https://ncbi.nlm.nih.gov/pubmed/19390784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-009-0026-2
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