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LAG-3 limits regulatory T cell proliferation and function in autoimmune diabetes

Inhibitory receptors are pivotal in controlling T cell homeostasis because of their intrinsic regulation of conventional effector T (Tconv) cell proliferation, viability and function. However, the role of Inhibitory receptors on regulatory T (Treg) cells remains obscure, as they could be required fo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Immunol
Hauptverfasser: Zhang, Qianxia, Chikina, Maria, Szymczak-Workman, Andrea L., Horne, William, Kolls, Jay K., Vignali, Kate M., Normolle, Daniel, Bettini, Maria, Workman, Creg J., Vignali, Dario A.A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5609824/
https://ncbi.nlm.nih.gov/pubmed/28783703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aah4569
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