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Regulatory T cells and inhibitory cytokines in autoimmunity

Foxp3(+) regulatory T cells (T(regs)) contribute significantly to the maintenance of peripheral tolerance, but they ultimately fail in autoimmune diseases. The events that lead to T(reg) failure in controlling autoreactive effector T cells (T(effs)) during autoimmunity are not completely understood....

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Bettini, Maria, Vignali, Dario A. A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787714/
https://ncbi.nlm.nih.gov/pubmed/19854631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2009.09.011
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