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CNS Destruction Mediated by GAD-Specific CD4(+) T Cells

High titers of autoantibodies against glutamic acid decarboxylase 65 (GAD65) are commonly observed in patients suffering from type 1 diabetes (T1D) as well as Stiff Person syndrome (SPS), a disorder that affects the central nervous system, and a variant of SPS, progressive encephalomyelitis with rig...

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Autori principali: Burton, Amanda R., Baquet, Zachary, Eisenbarth, George S., Tisch, Roland, Smeyne, Richard, Workman, Creg J., Vignali, Dario A.A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989406/
https://ncbi.nlm.nih.gov/pubmed/20348424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903728
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