Differential subcellular localization of the regulatory T-cell protein LAG-3 and the coreceptor CD4

CD4 binds to MHC class II molecules and enhances T-cell activation. The CD4-related transmembrane protein LAG-3 (lymphocyte activation gene-3, CD223) binds to the same ligand but inhibits T-cell proliferation. We have previously shown that LAG-3 cell surface expression is tightly regulated by extrac...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Woo, Seng-Ryong, Li, Nianyu, Bruno, Tullia C., Forbes, Karen, Brown, Scott, Workman, Creg, Drake, Charles G., Vignali, Dario A. A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987677/
https://ncbi.nlm.nih.gov/pubmed/20391435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200939874
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы