Preclinical Evaluation of Ureidosulfamate Carbonic Anhydrase IX/XII Inhibitors in the Treatment of Cancers

Autor Williams, Kaye J., Gieling, Roben G.
Vydáno v Int J Mol Sci (2019)

Hypoxia and oxidative stress in breast cancer: Tumour hypoxia – therapeutic considerations

Autor Williams, Kaye J, Cowen, Rachel L, Stratford, Ian J
Vydáno 2001

Hypoxia-Inducible Factor in Thyroid Carcinoma

Autor Burrows, Natalie, Babur, Muhammad, Resch, Julia, Williams, Kaye J., Brabant, Georg
Vydáno 2011

Radiation enhances the therapeutic effect of Banoxantrone in hypoxic tumour cells with elevated levels of nitric oxide synthase

Autor MEHIBEL, MANAL, SINGH, SIMENDRA, COWEN, RACHEL L., WILLIAMS, KAYE J., STRATFORD, IAN J.
Vydáno v Oncol Rep (2016)

Metabolic profiling reveals potential metabolic markers associated with Hypoxia Inducible Factor-mediated signalling in hypoxic cancer cells

Autor Armitage, Emily G., Kotze, Helen L., Allwood, J. William, Dunn, Warwick B., Goodacre, Royston, Williams, Kaye J.
Vydáno v Sci Rep (2015)

Irradiation Decreases the Neuroendocrine Biomarker Pro-Opiomelanocortin in Small Cell Lung Cancer Cells In Vitro and In Vivo

Autor Meredith, Suzanne L., Bryant, Jennifer L., Babur, Muhammad, Riddell, Philip W., Behrouzi, Roya, Williams, Kaye J., White, Anne
Vydáno v PLoS One (2016)

Preclinical dosimetry: exploring the use of small animal phantoms

Autor Biglin, Emma R., Price, Gareth J., Chadwick, Amy L., Aitkenhead, Adam H., Williams, Kaye J., Kirkby, Karen J.
Vydáno v Radiat Oncol (2019)

A novel untargeted metabolomics correlation-based network analysis incorporating human metabolic reconstructions

Autor Kotze, Helen L, Armitage, Emily G, Sharkey, Kieran J, Allwood, James W, Dunn, Warwick B, Williams, Kaye J, Goodacre, Royston
Vydáno 2013

The clinically active PARP inhibitor AG014699 ameliorates cardiotoxicity but doesn’t enhance the efficacy of doxorubicin, despite improving tumour perfusion and radiation response...

Autor Ali, Majid, Kamjoo, Marzieh, Thomas, Huw D, Kyle, Suzanne, Pavlovska, Ivanda, Babur, Muhammed, Telfer, Brian A, Curtin, Nicola J, Williams, Kaye J
Vydáno 2011

3D DESI-MS lipid imaging in a xenograft model of glioblastoma: a proof of principle

Autor Henderson, Fiona, Jones, Emrys, Denbigh, Joanna, Christie, Lidan, Chapman, Richard, Hoyes, Emmy, Claude, Emmanuelle, Williams, Kaye J., Roncaroli, Federico, McMahon, Adam
Vydáno v Sci Rep (2020)

Akt inhibition improves long‐term tumour control following radiotherapy by altering the microenvironment

Autor Searle, Emma J, Telfer, Brian A, Mukherjee, Debayan, Forster, Duncan M, Davies, Barry R, Williams, Kaye J, Stratford, Ian J, Illidge, Tim M
Vydáno v EMBO Mol Med (2017)

Hypoxia-Mediated Down-Regulation of Bid and Bax in Tumors Occurs via Hypoxia-Inducible Factor 1-Dependent and -Independent Mechanisms and Contributes to Drug Resistance

Autor Erler, Janine T., Cawthorne, Christopher J., Williams, Kaye J., Koritzinsky, Marianne, Wouters, Bradley G., Wilson, Clare, Miller, Crispin, Demonacos, Costas, Stratford, Ian J., Dive, Caroline
Vydáno 2004

Oxygen Enhanced Optoacoustic Tomography (OE-OT) Reveals Vascular Dynamics in Murine Models of Prostate Cancer

Autor Tomaszewski, Michal R, Gonzalez, Isabel Quiros, O'Connor, James PB, Abeyakoon, Oshaani, Parker, Geoff JM, Williams, Kaye J, Gilbert, Fiona J, Bohndiek, Sarah E
Vydáno v Theranostics (2017)

Glucocorticoid receptor over-expression promotes human small cell lung cancer apoptosis in vivo and thereby slows tumor growth

Autor Sommer, Paula, Cowen, Rachel L, Berry, Andrew, Cookson, Ann, Telfer, Brian A, Williams, Kaye J, Stratford, Ian J, Kay, Paul, White, Anne, Ray, David W
Vydáno 2010

N-tert-Prenylation of the indole ring improves the cytotoxicity of a short antagonist G analogue against small cell lung cancer

Autor Offerman, Shaun C., Kadirvel, Manikandan, Abusara, Osama H., Bryant, Jennifer L., Telfer, Brian A., Brown, Gavin, Freeman, Sally, White, Anne, Williams, Kaye J., Aojula, Harmesh S.
Vydáno v Medchemcomm (2017)

Inhibition of Monocarboxylate transporter-1 (MCT1) by AZD3965 enhances radiosensitivity by reducing lactate transport

Autor Bola, Becky M., Chadwick, Amy L., Michopoulos, Filippos, Blount, Kathryn G., Telfer, Brian A., Williams, Kaye J., Smith, Paul D, Critchlow, Susan E., Stratford, Ian J.
Vydáno v Mol Cancer Ther (2014)

Endothelial Heparan Sulfate 6-O-Sulfation Levels Regulate Angiogenic Responses of Endothelial Cells to Fibroblast Growth Factor 2 and Vascular Endothelial Growth Factor

Autor Ferreras, Cristina, Rushton, Graham, Cole, Claire L., Babur, Muhammad, Telfer, Brian A., van Kuppevelt, Toin H., Gardiner, John M., Williams, Kaye J., Jayson, Gordon C., Avizienyte, Egle
Vydáno 2012

Data‐driven mapping of hypoxia‐related tumor heterogeneity using DCE‐MRI and OE‐MRI

Autor Featherstone, Adam K., O'Connor, James P.B., Little, Ross A., Watson, Yvonne, Cheung, Sue, Babur, Muhammad, Williams, Kaye J., Matthews, Julian C., Parker, Geoff J.M.
Vydáno v Magn Reson Med (2017)

Statin-induced metabolic reprogramming in head and neck cancer: a biomarker for targeting monocarboxylate transporters

Autor Mehibel, Manal, Ortiz-Martinez, Fernando, Voelxen, Nadine, Boyers, Amy, Chadwick, Amy, Telfer, Brian A., Mueller-Klieser, Wolfgang, West, Catharine M., Critchlow, Susan E., Williams, Kaye J., Stratford, Ian J.
Vydáno v Sci Rep (2018)

Vasoactivity of AG014699, a clinically active small molecule inhibitor of poly(ADP-ribose) polymerase: a contributory factor to chemopotentiation in vivo?

Autor Ali, Majid, Telfer, Brian A, McCrudden, Cian, O’Rourke, Martin, Thomas, Huw D, Kamjoo, Marzieh, Kyle, Suzanne, Robson, Tracy, Shaw, Chris, Hirst, David G., Curtin, Nicola J, Williams, Kaye J
Vydáno 2009