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Metabolic profiling reveals potential metabolic markers associated with Hypoxia Inducible Factor-mediated signalling in hypoxic cancer cells

Hypoxia inducible factors (HIFs) plays an important role in oxygen compromised environments and therefore in tumour survival. In this research, metabolomics has been applied to study HIFs metabolic function in two cell models: mouse hepatocellular carcinoma and human colon carcinoma, whereby the met...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Armitage, Emily G., Kotze, Helen L., Allwood, J. William, Dunn, Warwick B., Goodacre, Royston, Williams, Kaye J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623531/
https://ncbi.nlm.nih.gov/pubmed/26508589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15649
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