The serine and threonine residues in the Ig-α cytoplasmic tail negatively regulate immunoreceptor tyrosine-based activation motif-mediated signal transduction

Por Müller, Ralph, Wienands, Jürgen, Reth, Michael
Publicado em 2000

Adapters in lymphocyte signaling

Por Leo, Albrecht, Wienands, Jürgen, Baier, Gottfried, Horejsi, Vaclav, Schraven, Burkhart
Publicado em 2002

SH3P7 Is a Cytoskeleton Adapter Protein and Is Coupled to Signal Transduction from Lymphocyte Antigen Receptors

Por Larbolette, Oliver, Wollscheid, Bernd, Schweikert, Jutta, Nielsen, Peter J., Wienands, Jürgen
Publicado em 1999

Epstein-Barr Virus Latent Membrane Protein 2a (Lmp2a) Employs the Slp-65 Signaling Module

Por Engels, Niklas, Merchant, Mark, Pappu, Rajita, Chan, Andrew C., Longnecker, Richard, Wienands, Jürgen
Publicado em 2001

SLP-65: A New Signaling Component in B Lymphocytes which Requires Expression of the Antigen Receptor for Phosphorylation

Por Wienands, Jürgen, Schweikert, Jutta, Wollscheid, Bernd, Jumaa, Hassan, Nielsen, Peter J., Reth, Michael
Publicado em 1998

SLP-65 Phosphorylation Dynamics Reveals a Functional Basis for Signal Integration by Receptor-proximal Adaptor Proteins

Por Oellerich, Thomas, Grønborg, Mads, Neumann, Konstantin, Hsiao, He-Hsuan, Urlaub, Henning, Wienands, Jürgen
Publicado em 2009

Epstein-Barr virus LMP2A signaling in statu nascendi mimics a B cell antigen receptor-like activation signal

Por Engels, Niklas, Yigit, Gökhan, Emmerich, Christoph H, Czesnik, Dirk, Schild, Detlev, Wienands, Jürgen
Publicado em 2012

STAT3: A Novel Molecular Mediator of Resistance to Chemoradiotherapy

Por Spitzner, Melanie, Ebner, Reinhard, Wolff, Hendrik A., Ghadimi, B. Michael, Wienands, Jürgen, Grade, Marian
Publicado no Cancers (Basel) (2014)

Reactivation of IgG-switched memory B cells by BCR-intrinsic signal amplification promotes IgG antibody production

Por Lutz, Johannes, Dittmann, Kai, Bösl, Michael R, Winkler, Thomas H, Wienands, Jürgen, Engels, Niklas
Publicado no Nat Commun (2015)

Subcellular localization of Grb2 by the adaptor protein Dok-3 restricts the intensity of Ca(2+) signaling in B cells

Por Stork, Björn, Neumann, Konstantin, Goldbeck, Ingo, Alers, Sebastian, Kähne, Thilo, Naumann, Michael, Engelke, Michael, Wienands, Jürgen
Publicado em 2007

The immunoglobulin tail tyrosine motif upgrades memory-type BCRs by incorporating a Grb2-Btk signalling module

Por Engels, Niklas, König, Lars M., Schulze, Wiebke, Radtke, Daniel, Vanshylla, Kanika, Lutz, Johannes, Winkler, Thomas H., Nitschke, Lars, Wienands, Jürgen
Publicado no Nat Commun (2014)

SH3P7/mAbp1 deficiency leads to tissue and behavioral abnormalities and impaired vesicle transport

Por Connert, Sabine, Wienand, Simone, Thiel, Cora, Krikunova, Maria, Glyvuk, Nataliya, Tsytsyura, Yaroslav, Hilfiker-Kleiner, Denise, Bartsch, Jörg W, Klingauf, Jürgen, Wienands, Jürgen
Publicado em 2006

The Dok-3/Grb2 Protein Signal Module Attenuates Lyn Kinase-dependent Activation of Syk Kinase in B Cell Antigen Receptor Microclusters

Por Lösing, Marion, Goldbeck, Ingo, Manno, Birgit, Oellerich, Thomas, Schnyder, Tim, Bohnenberger, Hanibal, Stork, Björn, Urlaub, Henning, Batista, Facundo D., Wienands, Jürgen, Engelke, Michael
Publicado em 2013

The B-cell antigen receptor signals through a preformed transducer module of SLP65 and CIN85

Por Oellerich, Thomas, Bremes, Vanessa, Neumann, Konstantin, Bohnenberger, Hanibal, Dittmann, Kai, Hsiao, He-Hsuan, Engelke, Michael, Schnyder, Tim, Batista, Facundo D, Urlaub, Henning, Wienands, Jürgen
Publicado em 2011

PI3K Inhibition Enhances Doxorubicin-Induced Apoptosis in Sarcoma Cells

Por Marklein, Diana, Graab, Ulrike, Naumann, Ivonne, Yan, Tiandong, Ridzewski, Rosalie, Nitzki, Frauke, Rosenberger, Albert, Dittmann, Kai, Wienands, Jürgen, Wojnowski, Leszek, Fulda, Simone, Hahn, Heidi
Publicado em 2012

Phage Display Based Cloning of Proteins Interacting with the Cytoplasmic Tail of Membrane Immunoglobulins

Por Geisberger, Roland, Prlic, Martin, Achatz-Straussberger, Gertrude, Oberndorfer, Iris, Luger, Elke, Lamers, Marinus, Crameri, Reto, Appenzeller, Ulrich, Wienands, Jürgen, Breitenbach, Michael, Ferreira, Fatima, Achatz, Gernot
Publicado em 2002

The intramembrane protease SPPL2a promotes B cell development and controls endosomal traffic by cleavage of the invariant chain

Por Schneppenheim, Janna, Dressel, Ralf, Hüttl, Susann, Lüllmann-Rauch, Renate, Engelke, Michael, Dittmann, Kai, Wienands, Jürgen, Eskelinen, Eeva-Liisa, Hermans-Borgmeyer, Irm, Fluhrer, Regina, Saftig, Paul, Schröder, Bernd
Publicado em 2013

Autoantibody-boosted T-cell reactivation in the target organ triggers manifestation of autoimmune CNS disease

Por Flach, Anne-Christine, Litke, Tanja, Strauss, Judith, Haberl, Michael, Gómez, César Cordero, Reindl, Markus, Saiz, Albert, Fehling, Hans-Jörg, Wienands, Jürgen, Odoardi, Francesca, Lühder, Fred, Flügel, Alexander
Publicado no Proc Natl Acad Sci U S A (2016)

The Intramembrane Proteases Signal Peptide Peptidase-Like 2a and 2b Have Distinct Functions In Vivo

Por Schneppenheim, Janna, Hüttl, Susann, Mentrup, Torben, Lüllmann-Rauch, Renate, Rothaug, Michelle, Engelke, Michael, Dittmann, Kai, Dressel, Ralf, Araki, Masatake, Araki, Kimi, Wienands, Jürgen, Fluhrer, Regina, Saftig, Paul, Schröder, Bernd
Publicado em 2014

Identification of Novel Nuclear Factor of Activated T Cell (NFAT)-associated Proteins in T Cells

Por Gabriel, Christian H., Gross, Fridolin, Karl, Martin, Stephanowitz, Heike, Hennig, Anna Floriane, Weber, Melanie, Gryzik, Stefanie, Bachmann, Ivo, Hecklau, Katharina, Wienands, Jürgen, Schuchhardt, Johannes, Herzel, Hanspeter, Radbruch, Andreas, Krause, Eberhard, Baumgrass, Ria
Publicado no J Biol Chem (2016)