SLP-65 Phosphorylation Dynamics Reveals a Functional Basis for Signal Integration by Receptor-proximal Adaptor Proteins

Understanding intracellular signal transduction by cell surface receptors requires information about the precise order of relevant modifications on the early transducer elements. Here we introduce the B cell line DT40 and its genetically engineered variants as a model system to determine and functio...

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Autors principals: Oellerich, Thomas, Grønborg, Mads, Neumann, Konstantin, Hsiao, He-Hsuan, Urlaub, Henning, Wienands, Jürgen
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2009
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709198/
https://ncbi.nlm.nih.gov/pubmed/19372136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M800567-MCP200
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