Sequential phosphorylation of SLP-76 at tyrosine 173 is required for activation of T and mast cells

Cooperatively assembled signalling complexes, nucleated by adaptor proteins, integrate information from surface receptors to determine cellular outcomes. In T and mast cells, antigen receptor signalling is nucleated by three adaptors: SLP-76, Gads and LAT. Three well-characterized SLP-76 tyrosine ph...

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Detalhes bibliográficos
Main Authors: Sela, Meirav, Bogin, Yaron, Beach, Dvora, Oellerich, Thomas, Lehne, Johanna, Smith-Garvin, Jennifer E, Okumura, Mariko, Starosvetsky, Elina, Kosoff, Rachelle, Libman, Evgeny, Koretzky, Gary, Kambayashi, Taku, Urlaub, Henning, Wienands, Jürgen, Chernoff, Jonathan, Yablonski, Deborah
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160187/
https://ncbi.nlm.nih.gov/pubmed/21725281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.213
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