The Intramembrane Proteases Signal Peptide Peptidase-Like 2a and 2b Have Distinct Functions In Vivo

We reported recently that the presenilin homologue signal peptide peptidase-like 2a (SPPL2a) is essential for B cell development by cleaving the N-terminal fragment (NTF) of the invariant chain (li, CD74). Based on this, we suggested that pharmacological modulation of SPPL2a may represent a novel ap...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Principais autores: Schneppenheim, Janna, Hüttl, Susann, Mentrup, Torben, Lüllmann-Rauch, Renate, Rothaug, Michelle, Engelke, Michael, Dittmann, Kai, Dressel, Ralf, Araki, Masatake, Araki, Kimi, Wienands, Jürgen, Fluhrer, Regina, Saftig, Paul, Schröder, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993588/
https://ncbi.nlm.nih.gov/pubmed/24492962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00038-14
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registros relacionados