Subcellular localization of Grb2 by the adaptor protein Dok-3 restricts the intensity of Ca(2+) signaling in B cells

por Stork, Björn, Neumann, Konstantin, Goldbeck, Ingo, Alers, Sebastian, Kähne, Thilo, Naumann, Michael, Engelke, Michael, Wienands, Jürgen
Publicado em 2007

The Dok-3/Grb2 Protein Signal Module Attenuates Lyn Kinase-dependent Activation of Syk Kinase in B Cell Antigen Receptor Microclusters

por Lösing, Marion, Goldbeck, Ingo, Manno, Birgit, Oellerich, Thomas, Schnyder, Tim, Bohnenberger, Hanibal, Stork, Björn, Urlaub, Henning, Batista, Facundo D., Wienands, Jürgen, Engelke, Michael
Publicado em 2013

DPP9 is a novel component of the N-end rule pathway targeting the tyrosine kinase Syk

por Justa-Schuch, Daniela, Silva-Garcia, Maria, Pilla, Esther, Engelke, Michael, Kilisch, Markus, Lenz, Christof, Möller, Ulrike, Nakamura, Fumihiko, Urlaub, Henning, Geiss-Friedlander, Ruth
Publicado no eLife (2016)

Tripartite phase separation of two signal effectors with vesicles priming B cell responsiveness

por Wong, Leo E., Bhatt, Arshiya, Erdmann, Philipp S., Hou, Zhen, Maier, Joachim, Pirkuliyeva, Sona, Engelke, Michael, Becker, Stefan, Plitzko, Jürgen, Wienands, Jürgen, Griesinger, Christian
Publicado no Nat Commun (2020)

The B-cell antigen receptor signals through a preformed transducer module of SLP65 and CIN85

por Oellerich, Thomas, Bremes, Vanessa, Neumann, Konstantin, Bohnenberger, Hanibal, Dittmann, Kai, Hsiao, He-Hsuan, Engelke, Michael, Schnyder, Tim, Batista, Facundo D, Urlaub, Henning, Wienands, Jürgen
Publicado em 2011

The intramembrane protease SPPL2a promotes B cell development and controls endosomal traffic by cleavage of the invariant chain

por Schneppenheim, Janna, Dressel, Ralf, Hüttl, Susann, Lüllmann-Rauch, Renate, Engelke, Michael, Dittmann, Kai, Wienands, Jürgen, Eskelinen, Eeva-Liisa, Hermans-Borgmeyer, Irm, Fluhrer, Regina, Saftig, Paul, Schröder, Bernd
Publicado em 2013

Global gene expression changes of in vitro stimulated human transformed germinal centre B cells as surrogate for oncogenic pathway activation in individual aggressive B cell lympho...

por Schrader, Alexandra, Meyer, Katharina, von Bonin, Frederike, Vockerodt, Martina, Walther, Neele, Hand, Elisabeth, Ulrich, Antje, Matulewicz, Kamila, Lenze, Dido, Hummel, Michael, Kieser, Arnd, Engelke, Michael, Trümper, Lorenz, Kube, Dieter
Publicado em 2012

The Intramembrane Proteases Signal Peptide Peptidase-Like 2a and 2b Have Distinct Functions In Vivo

por Schneppenheim, Janna, Hüttl, Susann, Mentrup, Torben, Lüllmann-Rauch, Renate, Rothaug, Michelle, Engelke, Michael, Dittmann, Kai, Dressel, Ralf, Araki, Masatake, Araki, Kimi, Wienands, Jürgen, Fluhrer, Regina, Saftig, Paul, Schröder, Bernd
Publicado em 2014

The MICA-129 dimorphism affects NKG2D signaling and outcome of hematopoietic stem cell transplantation

por Isernhagen, Antje, Malzahn, Dörthe, Viktorova, Elena, Elsner, Leslie, Monecke, Sebastian, von Bonin, Frederike, Kilisch, Markus, Wermuth, Janne Marieke, Walther, Neele, Balavarca, Yesilda, Stahl-Hennig, Christiane, Engelke, Michael, Walter, Lutz, Bickeböller, Heike, Kube, Dieter, Wulf, Gerald, Dressel, Ralf
Publicado no EMBO Mol Med (2015)

HSP90 promotes Burkitt lymphoma cell survival by maintaining tonic B-cell receptor signaling

por Walter, Roland, Pan, Kuan-Ting, Doebele, Carmen, Comoglio, Federico, Tomska, Katarzyna, Bohnenberger, Hanibal, Young, Ryan M., Jacobs, Laura, Keller, Ulrich, Bönig, Halvard, Engelke, Michael, Rosenwald, Andreas, Urlaub, Henning, Staudt, Louis M., Serve, Hubert, Zenz, Thorsten, Oellerich, Thomas
Publicado no Blood (2017)

Elucidation of tonic and activated B-cell receptor signaling in Burkitt’s lymphoma provides insights into regulation of cell survival

por Corso, Jasmin, Pan, Kuan-Ting, Walter, Roland, Doebele, Carmen, Mohr, Sebastian, Bohnenberger, Hanibal, Ströbel, Philipp, Lenz, Christof, Slabicki, Mikolaj, Hüllein, Jennifer, Comoglio, Federico, Rieger, Michael A., Zenz, Thorsten, Wienands, Jürgen, Engelke, Michael, Serve, Hubert, Urlaub, Henning, Oellerich, Thomas
Publicado no Proc Natl Acad Sci U S A (2016)