The MICA-129 dimorphism affects NKG2D signaling and outcome of hematopoietic stem cell transplantation

The MHC class I chain-related molecule A (MICA) is a highly polymorphic ligand for the activating natural killer (NK)-cell receptor NKG2D. A single nucleotide polymorphism causes a valine to methionine exchange at position 129. Presence of a MICA-129Met allele in patients (n = 452) undergoing hemato...

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Bibliografske podrobnosti
izdano v:EMBO Mol Med
Main Authors: Isernhagen, Antje, Malzahn, Dörthe, Viktorova, Elena, Elsner, Leslie, Monecke, Sebastian, von Bonin, Frederike, Kilisch, Markus, Wermuth, Janne Marieke, Walther, Neele, Balavarca, Yesilda, Stahl-Hennig, Christiane, Engelke, Michael, Walter, Lutz, Bickeböller, Heike, Kube, Dieter, Wulf, Gerald, Dressel, Ralf
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Ltd 2015
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4644379/
https://ncbi.nlm.nih.gov/pubmed/26483398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201505246
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