The intramembrane protease SPPL2c promotes male germ cell development by cleaving phospholamban

Signal peptide peptidase (SPP) and the four homologous SPP‐like (SPPL) proteases constitute a family of intramembrane aspartyl proteases with selectivity for type II‐oriented transmembrane segments. Here, we analyse the physiological function of the orphan protease SPPL2c, previously considered to r...

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Publicado no:EMBO Rep
Main Authors: Niemeyer, Johannes, Mentrup, Torben, Heidasch, Ronny, Müller, Stephan A, Biswas, Uddipta, Meyer, Rieke, Papadopoulou, Alkmini A, Dederer, Verena, Haug‐Kröper, Martina, Adamski, Vivian, Lüllmann‐Rauch, Renate, Bergmann, Martin, Mayerhofer, Artur, Saftig, Paul, Wennemuth, Gunther, Jessberger, Rolf, Fluhrer, Regina, Lichtenthaler, Stefan F, Lemberg, Marius K, Schröder, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399600/
https://ncbi.nlm.nih.gov/pubmed/30733280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201846449
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