The intramembrane protease SPPL2c promotes male germ cell development by cleaving phospholamban

Signal peptide peptidase (SPP) and the four homologous SPP‐like (SPPL) proteases constitute a family of intramembrane aspartyl proteases with selectivity for type II‐oriented transmembrane segments. Here, we analyse the physiological function of the orphan protease SPPL2c, previously considered to r...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO Rep
Prif Awduron: Niemeyer, Johannes, Mentrup, Torben, Heidasch, Ronny, Müller, Stephan A, Biswas, Uddipta, Meyer, Rieke, Papadopoulou, Alkmini A, Dederer, Verena, Haug‐Kröper, Martina, Adamski, Vivian, Lüllmann‐Rauch, Renate, Bergmann, Martin, Mayerhofer, Artur, Saftig, Paul, Wennemuth, Gunther, Jessberger, Rolf, Fluhrer, Regina, Lichtenthaler, Stefan F, Lemberg, Marius K, Schröder, Bernd
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2019
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399600/
https://ncbi.nlm.nih.gov/pubmed/30733280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201846449
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