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Epstein-Barr virus LMP2A signaling in statu nascendi mimics a B cell antigen receptor-like activation signal

BACKGROUND: The latent membrane protein (LMP) 2A of Epstein-Barr virus (EBV) is expressed during different latency stages of EBV-infected B cells in which it triggers activation of cytoplasmic protein tyrosine kinases. Early studies revealed that an immunoreceptor tyrosine-based activation motif (IT...

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Detalhes bibliográficos
Main Authors: Engels, Niklas, Yigit, Gökhan, Emmerich, Christoph H, Czesnik, Dirk, Schild, Detlev, Wienands, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352256/
https://ncbi.nlm.nih.gov/pubmed/22472181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-10-9
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