Molecular therapeutics in pancreas cancer

von Narayanan, Vignesh, Weekes, Colin D
Veröffentlicht in World J Gastrointest Oncol (2016)

The Many Faces of Wnt and Pancreatic Ductal Adenocarcinoma Oncogenesis

von Weekes, Colin D., Winn, Robert A.
Veröffentlicht 2011

The present and future of systemic and microenvironment-targeted therapy for pancreatic adenocarcinoma

von Mehta, Arnav, Hwang, William L., Weekes, Colin
Veröffentlicht in Ann Pancreat Cancer (2020)

A Phase Ib Study of Single‐Agent Idelalisib Followed by Idelalisib in Combination with Chemotherapy in Patients with Metastatic Pancreatic Ductal Adenocarcinoma

von Borazanci, Erkut, Pishvaian, Michael J., Nemunaitis, John, Weekes, Colin, Huang, Julie, Rajakumaraswamy, Nishanthan
Veröffentlicht in Oncologist (2020)

Refining the molecular framework for pancreatic cancer with single-cell and spatial technologies.

von Guo, Jimmy A., Hoffman, Hannah I., Weekes, Colin D., Zheng, Lei, Ting, David T., Hwang, William L.
Veröffentlicht in Clin Cancer Res (2021)

A phase 1b study evaluating the safety and pharmacokinetics of regorafenib in combination with cetuximab in patients with advanced solid tumors

von Weekes, Colin, Lockhart, A. Craig, Lee, James J., Sturm, Isrid, Cleton, Adriaan, Huang, Funan, Lenz, Heinz‐Josef
Veröffentlicht in Int J Cancer (2019)

Extracellular cyclophilin-A stimulates ERK1/2 phosphorylation in a cell-dependent manner but broadly stimulates nuclear factor kappa B

von Bahmed, Karim, Henry, Curtis, Holliday, Michael, Redzic, Jasmina, Ciobanu, Madalina, Zhang, Fengli, Weekes, Colin, Sclafani, Robert, DeGregori, James, Eisenmesser, Elan
Veröffentlicht 2012

Patient-derived tumour xenografts as models for oncology drug development

von Tentler, John J., Tan, Aik Choon, Weekes, Colin D., Jimeno, Antonio, Leong, Stephen, Pitts, Todd M., Arcaroli, John J., Messersmith, Wells A., Eckhardt, S. Gail
Veröffentlicht 2012

Utilization of Quantitative In Vivo Pharmacology Approaches to Assess Combination Effects of Everolimus and Irinotecan in Mouse Xenograft Models of Colorectal Cancer

von Bradshaw-Pierce, Erica L., Pitts, Todd M., Kulikowski, Gillian, Selby, Heather, Merz, Andrea L., Gustafson, Daniel L., Serkova, Natalie J., Eckhardt, S. Gail, Weekes, Colin D.
Veröffentlicht 2013

Clinical Translation of Ferumoxytol-Based Vessel Size Imaging (VSI): Feasibility in a Phase I Oncology Clinical Trial Population

von Fredrickson, Jill, Serkova, Natalie J., Wyatt, Shelby K., Carano, Richard A. D., Pirzkall, Andrea, Rhee, Ina, Rosen, Lee S., Bessudo, Alberto, Weekes, Colin, de Crespigny, Alex
Veröffentlicht in Magn Reson Med (2016)

A Phase Ib Study to Evaluate the MEK Inhibitor Cobimetinib in Combination with the ERK1/2 Inhibitor GDC‐0994 in Patients with Advanced Solid Tumors

von Weekes, Colin, Lockhart, Albert, LoRusso, Patricia, Murray, Elaine, Park, Erica, Tagen, Mike, Singh, Jatinder, Sarkar, Indrani, Mueller, Lars, Dokainish, Hatem, Shapiro, Geoffrey, Burris, Howard
Veröffentlicht in Oncologist (2020)

Stromal Cell-Derived Factor 1α Mediates Resistance to mTOR-Directed Therapy in Pancreatic Cancer

von Weekes, Colin D, Song, Dongweon, Arcaroli, John, Wilson, Lora A, Rubio-Viqueira, Belen, Cusatis, George, Garrett-Mayer, Elizabeth, Messersmith, Wells A, Winn, Robert A, Hidalgo, Manuel
Veröffentlicht 2012

Phase II trial of concurrent bevacizumab and transhepatic arterial chemoembolization in patients with unresectable hepatocellular carcinoma

von Buijs, Manon, Reyes, Diane K., Pawlik, Timothy M., Blackford, Amanda L., Salem, Riad, Messersmith, Wells A., Weekes, Colin D., Mulcahy, Mary, Kamel, Ihab R., Geschwind, Jean-Francois H.
Veröffentlicht 2012

Patterns of Care for Locally Advanced Pancreatic Adenocarcinoma Using the National Cancer Database

von Amini, Arya, Jones, Bernard L., Stumpf, Priscilla, Leong, Stephen, Lieu, Christopher H., Weekes, Colin, Davis, S. Lindsey, Messersmith, Wells A., Purcell, William T., Ghosh, Debashis, Schefter, Tracey, Goodman, Karyn A.
Veröffentlicht in Pancreas (2017)

A Phase I Dose‐Escalation Study of Linsitinib (OSI‐906), a Small‐Molecule Dual Insulin‐Like Growth Factor‐1 Receptor/Insulin Receptor Kinase Inhibitor, in Combination with Irinotec...

von Davis, S. Lindsey, Eckhardt, S. Gail, Diamond, Jennifer R., Messersmith, Wells A., Dasari, Arvind, Weekes, Colin D., Lieu, Christopher H., Kane, Madeline, Choon Tan, Aik, Pitts, Todd M., Leong, Stephen
Veröffentlicht in Oncologist (2018)

Thymidylate Synthase (TYMS) Enhancer Region Genotype-Directed Phase II Trial of Oral Capecitabine for 2nd Line Treatment of Advanced Pancreatic Cancer

von Weekes, Colin D., Nallapareddy, Sujatha, Rudek, Michelle A., Norris-Kirby, Alexis, Laheru, Daniel, Jimeno, Antonio, Donehower, Ross C., Murphy, Kathleen M., Hidalgo, Manuel, Baker, Sharyn D., Messersmith, Wells A.
Veröffentlicht 2010

hsa-miR29b, a critical downstream target of non-canonical Wnt signaling, plays an anti-proliferative role in non-small cell lung cancer cells via targeting MDM2 expression

von Avasarala, Sreedevi, Van Scoyk, Michelle, Wang, Jianbin, Sechler, Marybeth, Vandervest, Katherine, Brzezinski, Christine, Weekes, Colin, Edwards, Michael G., Arcaroli, John, Davis, Richard E., Bikkavilli, Rama Kamesh, Winn, Robert A.
Veröffentlicht 2013

CD147: a small molecule transporter ancillary protein at the crossroad of multiple hallmarks of cancer and metabolic reprogramming

von Kendrick, Agnieszka A., Schafer, Johnathon, Dzieciatkowska, Monika, Nemkov, Travis, D'Alessandro, Angelo, Neelakantan, Deepika, Ford, Heide L., Pearson, Chad G., Weekes, Colin D., Hansen, Kirk C., Eisenmesser, Elan Z.
Veröffentlicht in Oncotarget (2016)

Prognostic Factors of Survival in a Randomized Phase III Trial (MPACT) of Weekly nab-Paclitaxel Plus Gemcitabine Versus Gemcitabine Alone in Patients With Metastatic Pancreatic Can...

von Tabernero, Josep, Chiorean, E. Gabriela, Infante, Jeffrey R., Hingorani, Sunil R., Ganju, Vinod, Weekes, Colin, Scheithauer, Werner, Ramanathan, Ramesh K., Goldstein, David, Penenberg, Darryl N., Romano, Alfredo, Ferrara, Stefano, Von Hoff, Daniel D.
Veröffentlicht in Oncologist (2015)

Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma

von Grossberg, Aaron J., Chu, Linda C., Deig, Christopher R., Fishman, Eliot K., Hwang, William L., Maitra, Anirban, Marks, Daniel L., Mehta, Arnav, Nabavizadeh, Nima, Simeone, Diane M., Weekes, Colin D., Thomas, Charles R.
Veröffentlicht in CA Cancer J Clin (2020)