Molecular therapeutics in pancreas cancer

di Narayanan, Vignesh, Weekes, Colin D
Pubblicato in World J Gastrointest Oncol (2016)

The Many Faces of Wnt and Pancreatic Ductal Adenocarcinoma Oncogenesis

di Weekes, Colin D., Winn, Robert A.
Pubblicazione 2011

The present and future of systemic and microenvironment-targeted therapy for pancreatic adenocarcinoma

di Mehta, Arnav, Hwang, William L., Weekes, Colin
Pubblicato in Ann Pancreat Cancer (2020)

A Phase Ib Study of Single‐Agent Idelalisib Followed by Idelalisib in Combination with Chemotherapy in Patients with Metastatic Pancreatic Ductal Adenocarcinoma

di Borazanci, Erkut, Pishvaian, Michael J., Nemunaitis, John, Weekes, Colin, Huang, Julie, Rajakumaraswamy, Nishanthan
Pubblicato in Oncologist (2020)

Refining the molecular framework for pancreatic cancer with single-cell and spatial technologies.

di Guo, Jimmy A., Hoffman, Hannah I., Weekes, Colin D., Zheng, Lei, Ting, David T., Hwang, William L.
Pubblicato in Clin Cancer Res (2021)

A phase 1b study evaluating the safety and pharmacokinetics of regorafenib in combination with cetuximab in patients with advanced solid tumors

di Weekes, Colin, Lockhart, A. Craig, Lee, James J., Sturm, Isrid, Cleton, Adriaan, Huang, Funan, Lenz, Heinz‐Josef
Pubblicato in Int J Cancer (2019)

Extracellular cyclophilin-A stimulates ERK1/2 phosphorylation in a cell-dependent manner but broadly stimulates nuclear factor kappa B

di Bahmed, Karim, Henry, Curtis, Holliday, Michael, Redzic, Jasmina, Ciobanu, Madalina, Zhang, Fengli, Weekes, Colin, Sclafani, Robert, DeGregori, James, Eisenmesser, Elan
Pubblicazione 2012

Patient-derived tumour xenografts as models for oncology drug development

di Tentler, John J., Tan, Aik Choon, Weekes, Colin D., Jimeno, Antonio, Leong, Stephen, Pitts, Todd M., Arcaroli, John J., Messersmith, Wells A., Eckhardt, S. Gail
Pubblicazione 2012

Utilization of Quantitative In Vivo Pharmacology Approaches to Assess Combination Effects of Everolimus and Irinotecan in Mouse Xenograft Models of Colorectal Cancer

di Bradshaw-Pierce, Erica L., Pitts, Todd M., Kulikowski, Gillian, Selby, Heather, Merz, Andrea L., Gustafson, Daniel L., Serkova, Natalie J., Eckhardt, S. Gail, Weekes, Colin D.
Pubblicazione 2013

Clinical Translation of Ferumoxytol-Based Vessel Size Imaging (VSI): Feasibility in a Phase I Oncology Clinical Trial Population

di Fredrickson, Jill, Serkova, Natalie J., Wyatt, Shelby K., Carano, Richard A. D., Pirzkall, Andrea, Rhee, Ina, Rosen, Lee S., Bessudo, Alberto, Weekes, Colin, de Crespigny, Alex
Pubblicato in Magn Reson Med (2016)

A Phase Ib Study to Evaluate the MEK Inhibitor Cobimetinib in Combination with the ERK1/2 Inhibitor GDC‐0994 in Patients with Advanced Solid Tumors

di Weekes, Colin, Lockhart, Albert, LoRusso, Patricia, Murray, Elaine, Park, Erica, Tagen, Mike, Singh, Jatinder, Sarkar, Indrani, Mueller, Lars, Dokainish, Hatem, Shapiro, Geoffrey, Burris, Howard
Pubblicato in Oncologist (2020)

Stromal Cell-Derived Factor 1α Mediates Resistance to mTOR-Directed Therapy in Pancreatic Cancer

di Weekes, Colin D, Song, Dongweon, Arcaroli, John, Wilson, Lora A, Rubio-Viqueira, Belen, Cusatis, George, Garrett-Mayer, Elizabeth, Messersmith, Wells A, Winn, Robert A, Hidalgo, Manuel
Pubblicazione 2012

Phase II trial of concurrent bevacizumab and transhepatic arterial chemoembolization in patients with unresectable hepatocellular carcinoma

di Buijs, Manon, Reyes, Diane K., Pawlik, Timothy M., Blackford, Amanda L., Salem, Riad, Messersmith, Wells A., Weekes, Colin D., Mulcahy, Mary, Kamel, Ihab R., Geschwind, Jean-Francois H.
Pubblicazione 2012

Patterns of Care for Locally Advanced Pancreatic Adenocarcinoma Using the National Cancer Database

di Amini, Arya, Jones, Bernard L., Stumpf, Priscilla, Leong, Stephen, Lieu, Christopher H., Weekes, Colin, Davis, S. Lindsey, Messersmith, Wells A., Purcell, William T., Ghosh, Debashis, Schefter, Tracey, Goodman, Karyn A.
Pubblicato in Pancreas (2017)

A Phase I Dose‐Escalation Study of Linsitinib (OSI‐906), a Small‐Molecule Dual Insulin‐Like Growth Factor‐1 Receptor/Insulin Receptor Kinase Inhibitor, in Combination with Irinotec...

di Davis, S. Lindsey, Eckhardt, S. Gail, Diamond, Jennifer R., Messersmith, Wells A., Dasari, Arvind, Weekes, Colin D., Lieu, Christopher H., Kane, Madeline, Choon Tan, Aik, Pitts, Todd M., Leong, Stephen
Pubblicato in Oncologist (2018)

Thymidylate Synthase (TYMS) Enhancer Region Genotype-Directed Phase II Trial of Oral Capecitabine for 2nd Line Treatment of Advanced Pancreatic Cancer

di Weekes, Colin D., Nallapareddy, Sujatha, Rudek, Michelle A., Norris-Kirby, Alexis, Laheru, Daniel, Jimeno, Antonio, Donehower, Ross C., Murphy, Kathleen M., Hidalgo, Manuel, Baker, Sharyn D., Messersmith, Wells A.
Pubblicazione 2010

hsa-miR29b, a critical downstream target of non-canonical Wnt signaling, plays an anti-proliferative role in non-small cell lung cancer cells via targeting MDM2 expression

di Avasarala, Sreedevi, Van Scoyk, Michelle, Wang, Jianbin, Sechler, Marybeth, Vandervest, Katherine, Brzezinski, Christine, Weekes, Colin, Edwards, Michael G., Arcaroli, John, Davis, Richard E., Bikkavilli, Rama Kamesh, Winn, Robert A.
Pubblicazione 2013

CD147: a small molecule transporter ancillary protein at the crossroad of multiple hallmarks of cancer and metabolic reprogramming

di Kendrick, Agnieszka A., Schafer, Johnathon, Dzieciatkowska, Monika, Nemkov, Travis, D'Alessandro, Angelo, Neelakantan, Deepika, Ford, Heide L., Pearson, Chad G., Weekes, Colin D., Hansen, Kirk C., Eisenmesser, Elan Z.
Pubblicato in Oncotarget (2016)

Prognostic Factors of Survival in a Randomized Phase III Trial (MPACT) of Weekly nab-Paclitaxel Plus Gemcitabine Versus Gemcitabine Alone in Patients With Metastatic Pancreatic Can...

di Tabernero, Josep, Chiorean, E. Gabriela, Infante, Jeffrey R., Hingorani, Sunil R., Ganju, Vinod, Weekes, Colin, Scheithauer, Werner, Ramanathan, Ramesh K., Goldstein, David, Penenberg, Darryl N., Romano, Alfredo, Ferrara, Stefano, Von Hoff, Daniel D.
Pubblicato in Oncologist (2015)

Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma

di Grossberg, Aaron J., Chu, Linda C., Deig, Christopher R., Fishman, Eliot K., Hwang, William L., Maitra, Anirban, Marks, Daniel L., Mehta, Arnav, Nabavizadeh, Nima, Simeone, Diane M., Weekes, Colin D., Thomas, Charles R.
Pubblicato in CA Cancer J Clin (2020)