Thymidylate Synthase (TYMS) Enhancer Region Genotype-Directed Phase II Trial of Oral Capecitabine for 2nd Line Treatment of Advanced Pancreatic Cancer

PURPOSE: The primary aim of this study was to characterize the 6-month overall survival and toxicity associated with second-line capecitabine treatment of advanced pancreatic cancer patients harboring the TYMS *2/*2 allele. The secondary aim was to analyze the response rate and pharmacokinetics of c...

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Detalhes bibliográficos
Main Authors: Weekes, Colin D., Nallapareddy, Sujatha, Rudek, Michelle A., Norris-Kirby, Alexis, Laheru, Daniel, Jimeno, Antonio, Donehower, Ross C., Murphy, Kathleen M., Hidalgo, Manuel, Baker, Sharyn D., Messersmith, Wells A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110647/
https://ncbi.nlm.nih.gov/pubmed/20306339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-010-9413-7
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