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hsa-miR29b, a critical downstream target of non-canonical Wnt signaling, plays an anti-proliferative role in non-small cell lung cancer cells via targeting MDM2 expression

In non-small cell lung cancer cell lines, activation of β-catenin independent signaling, via Wnt7a/Frizzled9 signaling, leads to reversal of cellular transformation, reduced anchorage-independent growth and induction of epithelial differentiation. miRNA expression profiling on a human lung adenocarc...

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Podrobná bibliografie
Hlavní autoři: Avasarala, Sreedevi, Van Scoyk, Michelle, Wang, Jianbin, Sechler, Marybeth, Vandervest, Katherine, Brzezinski, Christine, Weekes, Colin, Edwards, Michael G., Arcaroli, John, Davis, Richard E., Bikkavilli, Rama Kamesh, Winn, Robert A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711035/
https://ncbi.nlm.nih.gov/pubmed/23862015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20134507
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